DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr5 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	74/367 - (20%)
Similarity:	119/367 - (32%)	Gaps:	121/367 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LIGKVIS-NSRAPQIAHEM--------------------------------LVEYFMALLVIMGL 53
            ||..||| .....|:||.:                                :||:|.     .|:
  Rat     8 LIASVISTRGLVAQVAHGLREEPEFVTARAGEGVVLRCDVIHPVTGQPPPYVVEWFK-----FGV 67

  Fly    54 TAPV----------------------DKQSRRSSQYFGHLAAAEELSNLIPD-NYDAI------- 88
            ..|:                      ||.|.|..|.........|...|:.| .||..
  Rat    68 PIPIFIKFGYYPPHVDPEYAGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVH 132

  Fly    89 -----DPVFDNTTDREVIAALGTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLA 148
                 .|.|..|..:.:.|..|.:..:.|.........|:|:::        |.:...:.:..::
  Rat   133 LTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKE--------GTLLSASGKYQVS 189

  Fly   149 RHIDNSDEWVLKIVSVQQRDAGVYECQVSTEPKISLAYKL---------VVVTSKAQILANRE-L 203
               |.|    |.:.||.:.|.|.|.|:         ||.:         ::|.....|::..| :
  Rat   190 ---DGS----LTVTSVSREDRGAYTCR---------AYSIQGEAVHTTHLLVQGPPFIVSPPENI 238

  Fly   204 FIQSGSDINLTCIAPQAPGPYTH-MLWHKDTELVSDSARGGIRVESEQQMKTSNLVISRVQHTDS 267
            .:....|..|||.|...||..|: ..|..:.....:..:..:|:     :....|:|.||:..|:
  Rat   239 TVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRI-----LIDGTLIIFRVKPEDA 298

  Fly   268 GNYTCSADNSNSDSVFVHIIKSEQHAAMQHELGSRLL-LPPL 308
            |.|||...||...|.......:.|:.|       |:| :||:
  Rat   299 GKYTCVPSNSLGRSPSASAYLTVQYPA-------RVLNMPPV 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	18/104 (17%)
		IG_like	98..179	CDD:214653	15/80 (19%)
		IG_like	206..278	CDD:214653	20/72 (28%)
		Ig	211..278	CDD:143165	19/67 (28%)
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273	11/78 (14%)
		I-set	139..225	CDD:369462	20/109 (18%)
		Ig	229..321	CDD:386229	24/96 (25%)
		Ig	<353..414	CDD:386229
		Ig	438..502	CDD:319273
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900