DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and rst

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001284835.1	Gene:	rst / 31290	FlyBaseID:	FBgn0003285	Length:	764	Species:	Drosophila melanogaster

Alignment Length:	246	Identity:	46/246 - (18%)
Similarity:	84/246 - (34%)	Gaps:	72/246 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 AALGTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNSDEWVLKIVSVQQ 166
            |.:|:...|.|.|.......:.||:.....:    :.|.||                 ...||..
  Fly   357 ADVGSVVSLTCEVDSNPQPEIVWIQHPSDRV----VGTSTN-----------------LTFSVSN 400

  Fly   167 RDAGVYECQVSTEPKISLAYKLVVVTSKAQILANRELFIQS--------------GSDINLTCIA 217
            ..||.|.|:.:             |...|:|.|:..::::.              |....:.|.|
  Fly   401 ETAGRYYCKAN-------------VPGYAEISADAYVYLKGSPAIGSQRTQYGLVGDTARIECFA 452

  Fly   218 PQAPGPYTHMLW------------HKDTELVSDSARGGIRVESEQQMKTSNLVISRVQHTDSGNY 270
            ...|.. .|:.|            | |..::.|:..||::         |.|:|...|....|.|
  Fly   453 SSVPRA-RHVSWTFNGQEISSESGH-DYSILVDAVPGGVK---------STLIIRDSQAYHYGKY 506

  Fly   271 TCSADNSNSDSVFVHIIKSEQHAAMQHELGSRLLLPPLPLLLLAVLLVVLL 321
            .|:..|...:.|....:::::..::...:...:.:... ||:|.:|:||.:
  Fly   507 NCTVVNDYGNDVAEIQLQAKKSVSLLMTIVGGISVVAF-LLVLTILVVVYI 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	16/88 (18%)
		IG_like	98..179	CDD:214653	16/76 (21%)
		IG_like	206..278	CDD:214653	19/97 (20%)
		Ig	211..278	CDD:143165	18/78 (23%)
rst	NP_001284835.1	IG_like	34..130	CDD:214653
		Ig	42..114	CDD:299845
		C2-set_2	135..225	CDD:285423
		Ig_3	265..329	CDD:290638
		I-set	346..420	CDD:254352	19/96 (20%)
		Ig	360..425	CDD:299845	19/98 (19%)
		Ig5_KIRREL3-like	428..524	CDD:143235	20/106 (19%)
		IG_like	435..524	CDD:214653	20/99 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810