DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and sdk

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001284756.1	Gene:	sdk / 31017	FlyBaseID:	FBgn0021764	Length:	2265	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	66/275 - (24%)
Similarity:	98/275 - (35%)	Gaps:	66/275 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 RRSSQYFGHLAAAEELSNLIPDNYDAIDPVFDNTTDREVIAALGT-TARLHC--RVRHLGDRAVS 123
            :..|..|.||       |:..|.|..:.|.. ....::|...:|| ...|.|  ..|.|.:....
  Fly   240 KEESSAFVHL-------NVSGDPYIEVAPEI-IVRPQDVKVKVGTGVVELQCIANARPLHELETL 296

  Fly   124 WIRQRDLHILTIGIMTYTNDQRFLARHIDNSDEW--VLKIVSVQQRDAGVYECQVSTEPKISLAY 186
            |::. .|.:.|.|:           ||..| |.|  .|.::......:|.|.|||...   |..|
  Fly   297 WLKD-GLAVETAGV-----------RHTLN-DPWNRTLALLQANSSHSGEYTCQVRLR---SGGY 345

  Fly   187 KLVVVTSKAQIL--------ANRELFIQSGSDINLTCIAPQAPGPYTHMLWHKDTELVSDSARGG 243
            ..|..:::.|||        ...|.|.:.|..:.|||.....|.|  .:.|.::.|.|......|
  Fly   346 PAVSASARLQILEPPLFFTPMRAETFGEFGGQVQLTCDVVGEPTP--QVKWFRNAESVDAHIESG 408

  Fly   244 IRVESEQQMKTSN-LVISRVQHTDSGNYTCSADN---SNSDSVFVHI--------IK-------- 288
                 ...:.|.| |||.::...|:..:.|.|.|   .||.|.::.:        :|
  Fly   409 -----RYTLNTDNTLVIKKLILDDAAMFQCLAINEAGENSASTWLRVKTKTAKNRVKRLAQPRIL 468

  Fly   289 --SEQHAAMQHELGS 301
              ...||.:..|.||
  Fly   469 RVRASHAGLGSEKGS 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	25/100 (25%)
		IG_like	98..179	CDD:214653	22/85 (26%)
		IG_like	206..278	CDD:214653	19/75 (25%)
		Ig	211..278	CDD:143165	18/70 (26%)
sdk	NP_001284756.1	Ig	71..157	CDD:299845
		I-set	72..150	CDD:254352
		Ig	172..245	CDD:299845	1/4 (25%)
		IG_like	280..356	CDD:214653	22/91 (24%)
		Ig	280..343	CDD:299845	19/78 (24%)
		IG_like	375..450	CDD:214653	22/81 (27%)
		Ig	378..447	CDD:143165	21/75 (28%)
		Ig	506..587	CDD:299845
		IG_like	506..587	CDD:214653
		I-set	592..682	CDD:254352
		Ig	595..682	CDD:299845
		FN3	686..789	CDD:238020
		FN3	798..893	CDD:238020
		FN3	901..1005	CDD:238020
		fn3	1011..1094	CDD:278470
		FN3	1108..1202	CDD:238020
		FN3	1210..1308	CDD:238020
		fn3	1317..1402	CDD:278470
		FN3	1415..1507	CDD:238020
		FN3	1513..1608	CDD:238020
		fn3	1617..1708	CDD:278470
		FN3	1722..1823	CDD:238020
		FN3	1828..1920	CDD:238020
		FN3	1927..2016	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810