DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and Tyro3

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_058788.1	Gene:	Tyro3 / 25232	RGDID:	3923	Length:	880	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	52/252 - (20%)
Similarity:	93/252 - (36%)	Gaps:	37/252 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 GTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNSDEWV--LKIVSVQQR 167
            |...:|:|.|..:.|..:.|::.        |.:.....|..::....|   |:  |.:.|.::.
  Rat    47 GQPVKLNCSVEGMDDPDIHWMKD--------GAVVQNASQVSISISEQN---WIGLLSLKSAERS 100

  Fly   168 DAGVYECQV--STEPKISLAYKLVVVTSKAQILANRELFIQSGSDINLTCIAPQAPGPYTHMLWH 230
            |||:|.|||  ..|.|||.:..|.|.......:..::|.:.......|:|.|...|.|.|...|.
  Rat   101 DAGLYWCQVKDGEETKISQSVWLTVEGVPFFTVEPKDLAVPPNVPFQLSCEAVGPPEPVTIFWWR 165

  Fly   231 KDTEL--------------VSDSARGGIRVESEQQMKTSNLVISRVQHTDSGNYTCSADNSNSDS 281
            ..|::              |:..........:.:.:.||...|.|:|...:..:..:....:|.:
  Rat   166 GPTKVGGPASSPSVLNVTGVTQRTEFSCEAHNIKGLATSRPAIIRLQAPPAAPFNITVTTISSSN 230

  Fly   282 VFVHIIKSEQHAAMQHELGSRLLLPPLPLLLLAVLLVV--------LLGPTSSLQIR 330
            ..|..:......|:.|....::...|.....|||::.|        .|.|.::..:|
  Rat   231 ASVAWVPGADGLALLHSCTVQVAHAPGEWEALAVVVPVPPFTCLLRNLAPATNYSLR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	24/89 (27%)
		IG_like	98..179	CDD:214653	19/77 (25%)
		IG_like	206..278	CDD:214653	14/85 (16%)
		Ig	211..278	CDD:143165	14/80 (18%)
Tyro3	NP_058788.1	IG_like	39..125	CDD:214653	24/88 (27%)
		IGc2	46..111	CDD:197706	19/74 (26%)
		Ig2_Tyro3_like	131..209	CDD:143226	12/77 (16%)
		IG_like	135..204	CDD:214653	10/68 (15%)
		FN3	215..307	CDD:238020	12/73 (16%)
		fn3	315..396	CDD:278470
		PTKc_Tyro3	498..781	CDD:270659
		Pkinase_Tyr	508..776	CDD:285015
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	804..827
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	842..864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910