DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr5 and Lrit3

DIOPT Version :9

Sequence 1:NP_650080.3 Gene:dpr5 / 41381 FlyBaseID:FBgn0037908 Length:336 Species:Drosophila melanogaster
Sequence 2:NP_001274153.1 Gene:Lrit3 / 242235 MGIID:2685267 Length:681 Species:Mus musculus


Alignment Length:298 Identity:64/298 - (21%)
Similarity:104/298 - (34%) Gaps:91/298 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MRWRHAVRATFTSTTATESSPLIGKV------ISNSRAPQIAHEMLVEYFMALLVIMGLTAPVDK 59
            :|..|.:|....|.||.....|:...      :.|:|...:.:|       |:..:..||. :|.
Mouse   104 LRQLHELRLDGNSLTAFPWVSLLDMPHLRTLDLHNNRIASVPNE-------AVRYLRNLTC-LDL 160

  Fly    60 QSRRSSQYFGHLAAAEELSNLIPDNYD-----AIDPVFDNTTD---REVIAALGTTARLHCRVRH 116
            .|.|             |:.|.||..|     |:.|  ..:.|   |.:|               
Mouse   161 SSNR-------------LTTLPPDFLDSWSHLAVTP--SRSPDFPPRRII--------------- 195

  Fly   117 LGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNSDEWVLKIVSVQQRDAGVYECQVSTEP- 180
            ||.:...|.  .|.||..:..::...|...:.  :|     .|.:.|..:|..|:...:|..|. 
Mouse   196 LGLQDNPWF--CDCHISKVIELSKVTDHAVVL--LD-----PLMVCSEPERFQGILFQRVELEKC 251

  Fly   181 -KISLAYKLVVVTSKAQILANRELFIQSGSDINLTCIAPQAPGPYTHMLWHK------DTELVSD 238
             |.|:......:||..            ||::.|.|.|...|.|  .:.|.:      :..::.:
Mouse   252 LKPSVMMSATKITSAL------------GSNVLLRCDAKGHPTP--QLTWTRSDGSTVNYTVIQE 302

  Fly   239 SARGGIRVESEQQMKTSNLVISRVQHTDSGNYTCSADN 276
            |...|||        .|.:.::.:.|.|:|:|.|.|.|
Mouse   303 SPGEGIR--------WSIISLTSISHKDAGDYRCKAKN 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr5NP_650080.3 V-set 95..191 CDD:284989 19/100 (19%)
IG_like 98..179 CDD:214653 15/80 (19%)
IG_like 206..278 CDD:214653 20/77 (26%)
Ig 211..278 CDD:143165 18/72 (25%)
Lrit3NP_001274153.1 LRR 1. /evidence=ECO:0000255 56..79
LRR_8 61..117 CDD:290566 3/12 (25%)
LRR 2. /evidence=ECO:0000255 80..103
leucine-rich repeat 83..106 CDD:275378 0/1 (0%)
LRR 3. /evidence=ECO:0000255 104..128 7/23 (30%)
LRR_8 105..165 CDD:290566 16/80 (20%)
LRR_4 106..146 CDD:289563 8/39 (21%)
leucine-rich repeat 107..130 CDD:275378 6/22 (27%)
LRR_4 129..170 CDD:289563 11/61 (18%)
LRR 4. /evidence=ECO:0000255 129..151 4/28 (14%)
leucine-rich repeat 131..154 CDD:275378 4/29 (14%)
LRR 5. /evidence=ECO:0000255 152..175 9/36 (25%)
leucine-rich repeat 155..168 CDD:275378 6/26 (23%)
Ig 254..335 CDD:299845 23/101 (23%)
IG_like 263..339 CDD:214653 22/92 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 350..391
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..464
FN3 489..563 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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