DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr5 and Ntm

DIOPT Version :9

Sequence 1:NP_650080.3 Gene:dpr5 / 41381 FlyBaseID:FBgn0037908 Length:336 Species:Drosophila melanogaster
Sequence 2:NP_001344522.1 Gene:Ntm / 235106 MGIID:2446259 Length:367 Species:Mus musculus


Alignment Length:345 Identity:75/345 - (21%)
Similarity:121/345 - (35%) Gaps:127/345 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 DAIDP-VFDNTTDREVIAALGTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLAR 149
            ||..| ..||.|.|:     |.:|.|.|.:.:...| |:|:.:..  ||..|...:..|.|.:. 
Mouse    35 DATFPKAMDNVTVRQ-----GESATLRCTIDNRVTR-VAWLNRST--ILYAGNDKWCLDPRVVL- 90

  Fly   150 HIDNSD-EWVLKIVSVQQRDAGVYECQVSTE--PKISLAYKLVVVTSKAQILANRELFIQSGSDI 211
             :.|:. ::.::|.:|...|.|.|.|.|.|:  ||.|..:.:|.|:.|. :..:.::.|..|::|
Mouse    91 -LSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKI-VEISSDISINEGNNI 153

  Fly   212 NLTCIA--------------PQAPG---------------------------------------- 222
            :|||||              |:|.|                                        
Mouse   154 SLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQSGEYECSASNDVAAPVVRRVKVT 218

  Fly   223 ------------------------------PYTHMLWHKDTELVSDSARGGIRVESEQQMKTSNL 257
                                          |.....|.||.:.:.:..: |::||:...:  |.|
Mouse   219 VNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVEGKK-GVKVENRPFL--SKL 280

  Fly   258 VISRVQHTDSGNYTCSADNS---NSDSVFVHIIKSEQHAAMQHELGSRLLLP---P--------- 307
            ....|...|.|||||.|.|.   .:.|:.:..:.....:.:..|:.:..|.|   |         
Mouse   281 TFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTLLQEVKTTALTPWKGPGAVSEVNNG 345

  Fly   308 ----------LPLLLLAVLL 317
                      ||||:|.:||
Mouse   346 TSRRAGCIWLLPLLVLHLLL 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr5NP_650080.3 V-set 95..191 CDD:284989 27/98 (28%)
IG_like 98..179 CDD:214653 21/81 (26%)
IG_like 206..278 CDD:214653 28/158 (18%)
Ig 211..278 CDD:143165 27/153 (18%)
NtmNP_001344522.1 Ig 44..132 CDD:416386 27/97 (28%)
Ig strand A' 44..49 CDD:409353 2/4 (50%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 3/6 (50%)
Ig strand C 64..70 CDD:409353 3/6 (50%)
CDR2 71..83 CDD:409353 3/13 (23%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 9/35 (26%)
Ig strand D 87..94 CDD:409353 1/8 (13%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 3/8 (38%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 136..205 CDD:404760 12/69 (17%)
Ig strand A' 144..148 CDD:409353 0/3 (0%)
Ig strand B 151..160 CDD:409353 5/8 (63%)
Ig strand F 197..205 CDD:409353 0/7 (0%)
Ig_3 222..299 CDD:404760 17/79 (22%)
putative Ig strand A 223..229 CDD:409353 0/5 (0%)
Ig strand B 239..243 CDD:409353 0/3 (0%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 2/3 (67%)
Ig strand F 292..297 CDD:409353 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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