DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	278	Identity:	63/278 - (22%)
Similarity:	100/278 - (35%)	Gaps:	65/278 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 DKQSRRSSQYFGHLAAAEELSNLIPD-NYDAI------------DPVFDNTTDREVIAALGTTAR 109
            ||.|.|..|.........|...|:.| .||..            .|.|..|..:.:.|..|.:..
Mouse    96 DKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSIT 160

  Fly   110 LHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARH--IDNSDEWVLKIVSVQQRDAGVY 172
            :.|.........|:|:::..|    :|..         |::  .|.|    |.:.||.:.|.|.|
Mouse   161 MTCTAFGNPKPIVTWLKEGTL----LGAS---------AKYQVSDGS----LTVTSVSREDRGAY 208

  Fly   173 ECQVSTEPKISLAYKL---------VVVTSKAQILANRE-LFIQSGSDINLTCIAPQAPGPYTH- 226
            .|:         ||.:         ::|.....|::..| :.:....|..|||.|...||..|:
Mouse   209 TCR---------AYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYT 264

  Fly   227 MLWHKDTELVSDSARGGIRVESEQQMKTSNLVISRVQHTDSGNYTCSADNSNSDSVFVHIIKSEQ 291
            ..|..:.....:..:..:|:     :....|:|.||:..|:|.|||...||...|.......:.|
Mouse   265 WYWQDENVYFQNDLKLRVRI-----LIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQ 324

  Fly   292 HAAMQHELGSRLL-LPPL 308
            :.|       |:| :||:
Mouse   325 YPA-------RVLNMPPV 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	20/106 (19%)
		IG_like	98..179	CDD:214653	17/82 (21%)
		IG_like	206..278	CDD:214653	20/72 (28%)
		Ig	211..278	CDD:143165	19/67 (28%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273	6/20 (30%)
		I-set	141..227	CDD:369462	22/111 (20%)
		Ig	231..323	CDD:386229	24/96 (25%)
		Ig	<355..416	CDD:386229
		Ig	440..504	CDD:319273
		FN3	512..607	CDD:238020
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900