DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and Ncam1

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	XP_006510118.1	Gene:	Ncam1 / 17967	MGIID:	97281	Length:	1162	Species:	Mus musculus

Alignment Length:	235	Identity:	48/235 - (20%)
Similarity:	87/235 - (37%)	Gaps:	60/235 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 IPDNYDAIDPVFDNTTDREVIAALGTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQR 145
            :|....|...:.:.|      |.||.:..|.|......:..:||.:..:         ...|::.
Mouse   210 VPPTVQARQSIVNAT------ANLGQSVTLVCDADGFPEPTMSWTKDGE---------PIENEEE 259

  Fly   146 FLARHIDNSDEWVLKIVSVQQRDAGVYEC---------------QVSTEPKISLAYKLVVVTSKA 195
            ...:||.:.|...|.|.:|.:.|...|.|               :|..:|||:.......:..:.
Mouse   260 DDEKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEE 324

  Fly   196 QILANRELFIQSGSDINLTCIAPQAPGPYTHMLWHKDTELVSDSARGG-IRVESEQQM------- 252
            |              :.|||.|...|.|  .:.|...|..:|...:.. .|.|.::.:
Mouse   325 Q--------------VTLTCEASGDPIP--SITWRTSTRNISSEEKASWTRPEKQETLDGHMVVR 373

  Fly   253 ---KTSNLVISRVQHTDSGNYTCSADNS---NSDSVFVHI 286
               :.|:|.:..:|:||:|.|.|:|.|:   :|.|:::.:
Mouse   374 SHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	22/110 (20%)
		IG_like	98..179	CDD:214653	18/95 (19%)
		IG_like	206..278	CDD:214653	21/85 (25%)
		Ig	211..278	CDD:143165	21/80 (26%)
Ncam1	XP_006510118.1	Ig1_NCAM-1	20..115	CDD:143273
		IG	124..190	CDD:214652
		Ig3_NCAM-1_like	211..308	CDD:143207	21/111 (19%)
		Ig_NCAM-1	307..413	CDD:143277	27/121 (22%)
		Ig_3	417..494	CDD:372822
		FN3	509..606	CDD:238020
		fn3	649..731	CDD:365830
		PHA03247	<905..1140	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900