DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and Kirrel

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus

Alignment Length:	205	Identity:	50/205 - (24%)
Similarity:	82/205 - (40%)	Gaps:	54/205 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 DREVIAALGTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLA-----------RH 150
            |:.|:|  |..|.|.|.:.:..                 ||:.:|.|...|.           |.
Mouse    61 DQTVVA--GQRAVLPCVLLNYS-----------------GIVQWTKDGLALGMGQGLKAWPRYRV 106

  Fly   151 IDNSD--EWVLKIVSVQQRDAGVYECQVSTEPKISLAYKLVVV--TSKAQILANRELFIQSGSDI 211
            :.::|  ::.|:|...:..|...||||.:.....|...||.|:  ..:.:|.....:.:|:|:..
Mouse   107 VGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPY 171

  Fly   212 NLTCIAPQAPGPYTHMLWHKD----------TELVSDSARGGIRVESEQQMKTSNLVISRVQHTD 266
            ||||.|..|. |...::|.:|          |||:.|..|.  ...|:..::.::|.|.||
Mouse   172 NLTCRAFNAK-PAATIIWFRDGTQQEGAVTSTELLKDGKRE--TTISQLLIEPTDLDIGRV---- 229

  Fly   267 SGNYTCSADN 276
               :||.:.|
Mouse   230 ---FTCRSMN 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	24/106 (23%)
		IG_like	98..179	CDD:214653	20/93 (22%)
		IG_like	206..278	CDD:214653	24/81 (30%)
		Ig	211..278	CDD:143165	22/76 (29%)
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	24/105 (23%)
		Ig2_KIRREL3-like	170..251	CDD:143236	22/77 (29%)
		Ig	255..336	CDD:386229
		Ig_3	340..421	CDD:372822
		Ig5_KIRREL3	439..536	CDD:143306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810