Protein Alignment dpr5 and iglon5

DIOPT Version :10

• Sequence 1: NP_650080.3
• Gene: dpr5 / 41381
• FlyBaseID: FBgn0037908
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: XP_002938252.1
• Gene: iglon5 / 100488314
• XenbaseID: XB-GENE-945713
• Length: 333
• Species: Xenopus tropicalis
• Alignment Length: 378
• Identity: 84/378 - (22%)
• Similarity: 125/378 - (33%)
• Gaps: 146/378 - (38%)

  Fly    53 LTAPVDKQSRRSSQYFGHLAAAEEL----SNLIP--DNYDAIDPVFDNTTDREVIAALGTTARLH 111
            :.||:.:.|..|   .|.:..|:.|    :..:|  |||               ..:.|..|.|.
 Frog     1 MKAPLQRVSLAS---LGIVMLAQVLFVQCTEFVPPADNY---------------TVSQGDNATLS 47

  Fly   112 CRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNS-DEWVLKIVSVQQRDAGVYECQ 175
            |.:.....| |:|:.:.  :||..|...::.|.|  .:.:.|: .|:.:.|..|...|.|:|.|.
 Frog    48 CLIDDKVTR-VAWLNRS--NILYAGKDKWSIDSR--VQLLTNTKSEYSIVITHVDVADEGLYTCS 107

  Fly   176 VSTE--PKISLAYKLVVVTSKAQILANRELFIQSGSDINLTCIAPQAPGP--------------- 223
            ..||  |..|..|.:|.|.:|. :..:..:.:..||::||.|:|...|.|
 Frog   108 FQTEDKPHTSQVYLIVQVPAKI-VNISSSVTVNEGSNVNLQCLAVGKPEPTITWQQLSEGFSSEG 171

  Fly   224 -------------------------------------YTHML----------------------- 228
                                                 |...:
 Frog   172 ELLEITEINRQQAGDYECVTSNGVSVPDTKKVQITVNYPPYITDVKNAQSPVGRPATLRCKAMAV 236

  Fly   229 ------WHKDTELVSDSARGGIRVESEQQMKTSNLVISRVQHTDSGNYTCSADNSNSDSVFVHII 287
                  |:||.:....|...|:.:::|...  |.:|.|.|.....|||||.|.|
 Frog   237 PPAEFEWYKDEKRRLISGTEGLSIKTESSW--SVIVFSNVTSRHYGNYTCLASN----------- 288

  Fly   288 KSEQHAAMQHELGS-----RLLLPPLPLLLLAVLLV--VLLGPTSSLQIRTPL 333
                      :|||     |||.|..||...|..:|  :|||..||..|  ||
 Frog   289 ----------KLGSFNSSLRLLKPGDPLNQGATHMVSPLLLGLLSSTLI--PL 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	FR1	96..113	CDD:409355	3/16 (19%)
		IG_like	98..179	CDD:214653	20/81 (25%)
		Ig strand A'	100..102	CDD:409355	0/1 (0%)
		Ig strand B	106..114	CDD:409355	3/7 (43%)
		CDR1	114..120	CDD:409355	0/5 (0%)
		FR2	121..132	CDD:409355	2/10 (20%)
		Ig strand C	121..127	CDD:409355	2/5 (40%)
		Ig strand C'	130..133	CDD:409355	0/2 (0%)
		CDR2	133..146	CDD:409355	3/12 (25%)
		Ig strand D	146..151	CDD:409355	0/4 (0%)
		FR3	147..176	CDD:409355	8/29 (28%)
		Ig strand E	155..162	CDD:409355	1/6 (17%)
		Ig strand F	170..177	CDD:409355	3/6 (50%)
		IG_like	206..278	CDD:214653	26/152 (17%)
		Ig strand B	211..215	CDD:409353	2/3 (67%)
		Ig strand C	226..230	CDD:409353	0/32 (0%)
		Ig strand E	255..259	CDD:409353	1/3 (33%)
		Ig strand F	269..274	CDD:409353	4/4 (100%)
iglon5	XP_002938252.1	Ig	31..123	CDD:472250	29/111 (26%)
		Ig strand B	44..48	CDD:409353	2/3 (67%)
		Ig strand C	56..60	CDD:409353	2/4 (50%)
		Ig strand E	89..93	CDD:409353	0/3 (0%)
		Ig strand F	103..108	CDD:409353	2/4 (50%)
		Ig strand G	116..119	CDD:409353	1/2 (50%)
		Ig	122..207	CDD:472250	11/85 (13%)
		Ig strand B	144..148	CDD:409353	2/3 (67%)
		Ig strand C	157..160	CDD:409353	0/2 (0%)
		Ig strand E	172..176	CDD:409353	0/3 (0%)
		Ig strand F	186..191	CDD:409353	0/4 (0%)
		Ig strand G	200..203	CDD:409353	0/2 (0%)
		Ig_3	210..288	CDD:464046	16/79 (20%)