DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PGRP-LB and Pglyrp2

DIOPT Version :9

Sequence 1:	NP_001247052.1	Gene:	PGRP-LB / 41379	FlyBaseID:	FBgn0037906	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_006524773.1	Gene:	Pglyrp2 / 57757	MGIID:	1928099	Length:	544	Species:	Mus musculus

Alignment Length:	250	Identity:	87/250 - (34%)
Similarity:	127/250 - (50%)	Gaps:	42/250 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GDKV--------SGSVSTSGPT-------SLAIL--MDSEQLEQQQLATSCGYSQHMQQANLGDG 49
            ||.|        :|:..||.||       :|.:|  ::.|.|:.|.::    ..|..|.|.|...
Mouse   290 GDPVFRSNFRRQNGAALTSAPTLAQQVWEALVLLQKLEPEHLQLQNIS----QEQLAQVATLATK 350

  Fly    50 VATARLLS------RSDWGARLPKSVEHFQG-PAP------YVIIHHSYMPA-VCYSTPDCMKSM 100
            ..|...|.      |..|||      ..::| |.|      ::.:||:|:|| .|.:...|...|
Mouse   351 EFTEAFLGCPAIHPRCRWGA------APYRGHPTPLRLPLGFLYVHHTYVPAPPCTTFQSCAADM 409

  Fly   101 RDMQDFHQLERGWNDIGYSFGIGGDGMIYTGRGFNVIGAHAPKYNDKSVGIVLIGDWRTELPPKQ 165
            |.||.|||..|.|:||||||.:|.||.:|.|||::.:|||...||.:..|:..:|::...||.:.
Mouse   410 RSMQRFHQDVRKWDDIGYSFVVGSDGYLYQGRGWHWVGAHTRGYNSRGFGVAFVGNYTGSLPNEA 474

  Fly   166 MLDAAKN-LIAFGVFKGYIDPAYKLLGHRQVRDTECPGGRLFAEISSWPHFTHIN 219
            .|:..:: |.:..:..|.:.|.||||||||:..|.|||..||..:.:|||||.::
Mouse   475 ALNTVRDALPSCAIRAGLLRPDYKLLGHRQLVLTHCPGNALFNLLRTWPHFTEVS 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LB	NP_001247052.1	PGRP	53..195	CDD:128941	57/156 (37%)
Pglyrp2	XP_006524773.1	PGRP	360..505	CDD:128941	56/150 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	115	1.000	Domainoid score	I6007
eggNOG	1	0.900	-	-		E1_2CMNT
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H49671
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101717
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9951
SonicParanoid	1	1.000	-	-		X5082
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.710