DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGRP-LB and pglyrp2

DIOPT Version :9

Sequence 1:	NP_001247052.1	Gene:	PGRP-LB / 41379	FlyBaseID:	FBgn0037906	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001038631.1	Gene:	pglyrp2 / 568634	ZFINID:	ZDB-GENE-071227-1	Length:	458	Species:	Danio rerio

Alignment Length:	217	Identity:	73/217 - (33%)
Similarity:	110/217 - (50%)	Gaps:	21/217 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DKVSGSVSTSGPTSLAILMDSEQLEQQQLATSCGYSQHMQQANLGDGVATARLLSRSDWGARLPK 67
            :||:|.:.:.|...|..|:.....|.......|                 ..::.|..|||..|:
Zfish   252 EKVAGVLPSQGDAELESLIAKGIKEFVLRYMDC-----------------PSIIPRCIWGAAPPQ 299

  Fly    68 -SVEHFQGPAPYVIIHHSYMPA-VCYSTPDCMKSMRDMQDFHQLERGWNDIGYSFGIGGDGMIYT 130
             .:|....|..::.|||:.:|: .|.:...|.::||.||.|||.:.||.||||||.:|.||.||.
Zfish   300 VPLELLSPPMSFLYIHHTAIPSKPCLNLQTCSQNMRAMQRFHQKDWGWYDIGYSFVVGSDGYIYE 364

  Fly   131 GRGFNVIGAHAPKYNDKSVGIVLIGDWRTELPPKQMLDAAK-NLIAFGVFKGYIDPAYKLLGHRQ 194
            |||:...|||....|:...|:..|||:...||....::..: :|:..||..|::...:.:|||||
Zfish   365 GRGWMSQGAHTKGRNNVGYGVAFIGDYSGRLPSTHDMELVRHHLVKCGVNNGFLQEDFTILGHRQ 429

  Fly   195 -VRDTECPGGRLFAEISSWPHF 215
             |..|.|||..|::||::|.|:
Zfish   430 VVVTTSCPGNALYSEITTWMHY 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LB	NP_001247052.1	PGRP	53..195	CDD:128941	55/145 (38%)
pglyrp2	NP_001038631.1	PGRP	285..430	CDD:128941	54/144 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CMNT
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H49671
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101717
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9951
SonicParanoid	1	1.000	-	-		X5082
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.710