Protein Alignment PGRP-LB and PGLYRP2

DIOPT Version :9

• Sequence 1: NP_001247052.1
• Gene: PGRP-LB / 41379
• FlyBaseID: FBgn0037906
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_001350475.1
• Gene: PGLYRP2 / 114770
• HGNCID: 30013
• Length: 634
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 84/254 - (33%)
• Similarity: 123/254 - (48%)
• Gaps: 43/254 - (16%)

  Fly    15 TSLAILMDS--------EQLEQQQLATSCGYSQHMQQANLGDGVATA------------RLLSRS 59
            ||.:||...        ::||...|...|     |.|..|....|.|            .:..|.
Human   327 TSASILAQQVWGTLVLLQRLEPVHLQLQC-----MSQEQLAQVAANATKEFTEAFLGCPAIHPRC 386

  Fly    60 DWGAR----LPKSVEHFQGPAPYVIIHHSYMPA-VCYSTPDCMKSMRDMQDFHQLERGWNDIGYS 119
            .|||.    .||.:   |.|..::.:||:|:|| .|.....|..:||.||.:||..:||.|||||
Human   387 RWGAAPYRGRPKLL---QLPLGFLYVHHTYVPAPPCTDFTRCAANMRSMQRYHQDTQGWGDIGYS 448

  Fly   120 FGIGGDGMIYTGRGFNVIGAHAPKYNDKSVGIVLIGDWRTELPPKQMLDAAKN-LIAFGVFKGYI 183
            |.:|.||.:|.|||::.:|||...:|.:..|:.::|::...||.:..|...:: |.:..|..|.:
Human   449 FVVGSDGYVYEGRGWHWVGAHTLGHNSRGFGVAIVGNYTAALPTEAALRTVRDTLPSCAVRAGLL 513

  Fly   184 DPAYKLLGHRQVRDTECPGGRLFAEISSWPHFTHIN---------DTEGVSSTTAPVVP 233
            .|.|.||||||:..|:|||..||..:.:|||||.::         .....:|:|.|:.|
Human   514 RPDYALLGHRQLVRTDCPGDALFDLLRTWPHFTAVSLRSLHYTARRPSVYTSSTRPLPP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LB	NP_001247052.1	PGRP	53..195	CDD:128941	56/159 (35%)
PGLYRP2	NP_001350475.1	PGRP	380..525	CDD:128941	55/147 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CMNT
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H49671
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7130
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101717
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9951
SonicParanoid	1	1.000	-	-		X5082
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.660