Protein Alignment Exd2 and Exd2

DIOPT Version :10

• Sequence 1: NP_650075.1
• Gene: Exd2 / 41374
• FlyBaseID: FBgn0037901
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_598559.2
• Gene: Exd2 / 97827
• MGIID: 1922485
• Length: 650
• Species: Mus musculus
• Alignment Length: 588
• Identity: 225/588 - (38%)
• Similarity: 327/588 - (55%)
• Gaps: 90/588 - (15%)

  Fly    36 PLRRVW--------SFGSLVPQR--------RIEVINSVQDPTTQWVLNELKNHCQTFKVLGFDC 84
            |..|.|        .||:|...|        :.||:...|:.....:...||...:.|.|||.||
Mouse    74 PGGREWPPPEDDQLPFGALRAPRASWEERILQAEVVTVSQEAEWNQIQPFLKRELEDFPVLGIDC 138

  Fly    85 EWITVGGSRRPVALLQLSSHRGLCALFRLCHM----KQIPQDLRELLEDDSVIKVGVAPQEDAMK 145
            ||:.:.|...|::|||::|..|.|||.||..:    :.:|:.|.::|.|.:::||||...|||.|
Mouse   139 EWVNLEGKASPLSLLQMASPSGFCALVRLPRLIYGGRTLPRTLLDILADGAILKVGVGCSEDANK 203

  Fly   146 LSHDYGVGVASTLDLRFLCVMAGHK--PEGLG--KLSKTHLNYTLDKHWRLACSNWEAKTLEPKQ 206
            |..|||:.|...||||:|.:..|:.  ..||.  .|::|.||:.|||...|.||||:|:.|...|
Mouse   204 LLQDYGLIVRGCLDLRYLAMKQGNNILCNGLSLKSLAETILNFPLDKSLLLRCSNWDAENLTEDQ 268

  Fly   207 LDYAANDALMAVAIYQKLCRDLQPKHFWQRRQLDDNSMHNKFE---PFLDVDFTKGFTLNPSGSG 268
            :.|||.||.::||::..|......:..::....|..:.....|   ..:|:.|
Mouse   269 VTYAARDAQISVALFLHLLGYPFSRDSYEEESTDQINWQKALERCRNMVDIPF------------ 321

  Fly   269 VTRSKG--------------------STQSKSNKWVP-----------KKQP----YRQIATRTK 298
              ||||                    :.::|:::.||           |::|    |   :.|..
Mouse   322 --RSKGLGRLVEEVNGEALESQLKPRNRKAKTDRMVPGNNQGRDPRKHKRKPLGVGY---SARKS 381

  Fly   299 DFYDNCLLQAPDGELLCTIDRRKASWYLNQNLGTHISEEPFTVRLNFEPAGRAVGDVGRFYQTIK 363
            ..||||.||||||:.|||.|||||.|||::.:|..:|:|||.|||.||||||.... |.:|..:|
Mouse   382 PLYDNCFLQAPDGQPLCTCDRRKAQWYLDKGIGELVSKEPFVVRLQFEPAGRPESP-GDYYLMVK 445

  Fly   364 KNQCVVCGDRDAYIRKNVVPREYRKHFPLVMKSHTSDDVLLLCPTCHQLSNISDLRVRSKLAVQC 428
            :|.|||||..|.|||||::|.|||||||:.||.|.|.||||||.:||.:||..|..::.:||.:.
Mouse   446 ENLCVVCGKTDTYIRKNIIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEF 510

  Fly   429 EAPFKQEDGSVKYHDDPQLKRVQSAGKALLHHGAKIPAAKKAEMEKTLLDYYSDQTD-ITEDLLR 492
            :||...|:| ::..:|.:.::|:|..:||| :...:||.:|.|:...|.::|:  || |||::|.
Mouse   511 QAPIGSEEG-LRLLEDLERRQVRSGARALL-NAESLPAHRKEELLHALREFYN--TDIITEEMLH 571

  Fly   493 QAASVEYRVENSDYCQHGERVVQQYRDHFGG---LVELERLWRQHFLHTMQPRFLPELWNVNHNA 554
            :|||:|.|:.|..|..||.:|||::.:  ||   |::||..||||||.:|||:.||:.|:|:||.
Mouse   572 EAASLETRIYNESYIPHGLKVVQRHTE--GGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNH 634

  Fly   555 DRL 557
            .:|
Mouse   635 QKL 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Exd2	NP_650075.1	WRN_exo	62..226	CDD:176653	70/171 (41%)
Exd2	NP_598559.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..89		7/30 (23%)
		WRN_exo	111..287	CDD:176653	69/183 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..373		21/32 (66%)