Protein Alignment CG5270 and PLEKHF2

DIOPT Version :9

• Sequence 1: NP_731570.2
• Gene: CG5270 / 41370
• FlyBaseID: FBgn0037897
• Length: 2243
• Species: Drosophila melanogaster
• Sequence 2: NP_078889.1
• Gene: PLEKHF2 / 79666
• HGNCID: 20757
• Length: 249
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 58/238 - (24%)
• Similarity: 90/238 - (37%)
• Gaps: 55/238 - (23%)

  Fly  1328 CFDKTGHVYDVQSSAGLGSGA------GETPAKIRFQLGQTTSEAFILLNFNSYQQDHFVG---- 1382
            ||...|....:.....:|.|.      .:..|:..|..........|::....|.:.|.:.
Human    21 CFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENV 85

  Fly  1383 -----QDCLDL----LLRIYASKALDYHVANVRAASEPSSLGTDVHNSLDSLCGAFVMPK--QAP 1436
                 :|..||    |::. .:|:...:.|   .|:|.|.....::.     |...::.|  :.|
Human    86 TIDSIKDEGDLRNGWLIKT-PTKSFAVYAA---TATEKSEWMNHINK-----CVTDLLSKSGKTP 141

  Fly  1437 NRQQ---WTRDEEASHCMCCRRAAFTMLMRRHHCRRCGRVVCYACSTHRIRIPELYDELEVRICN 1498
            :.:.   |..|.||:.||.|::|.||.:.||||||:||.|||..||..|..:|. .....||||:
Human   142 SNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPS-QSSKPVRICD 205

  Fly  1499 DC---------AAC------------STPAKDQGDGTSSERSA 1520
            .|         |.|            .:|..|..|....:.|:
Human   206 FCYDLLSAGDMATCQPARSDSYSQSLKSPLNDMSDDDDDDDSS 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5270	NP_731570.2	PHD_SF	1441..1500	CDD:304600	29/58 (50%)
PLEKHF2	NP_078889.1	PH_Phafin2-like	7..129	CDD:269927	19/116 (16%)
		FYVE_PKHF2	148..211	CDD:277294	30/63 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..249		4/28 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1237900at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920