DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaG and AT1G12570

DIOPT Version :9

Sequence 1:	NP_650070.1	Gene:	ninaG / 41369	FlyBaseID:	FBgn0037896	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_172718.2	Gene:	AT1G12570 / 837814	AraportID:	AT1G12570	Length:	572	Species:	Arabidopsis thaliana

Alignment Length:	604	Identity:	148/604 - (24%)
Similarity:	239/604 - (39%)	Gaps:	139/604 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 FDYVIVGGGTGGSTLTSLLAKNSNGSVLLIEAGGQFGLLSRIPLLTTFQQKGINDWSFLSVPQKH 111
            :||:|:||||.|..|.:.|::|:  ||||:|.|........|..|:.| ...::|.|..|..|:.
plant    46 YDYIIIGGGTAGCPLAATLSQNA--SVLLLERGDSPYNNPNITRLSAF-GAALSDLSESSPSQRF 107

  Fly   112 -SSRGLIERRQCLPRGKGLGGSANLN----------YMLHFDGHGPDFDSWRDHHNLSDWSWAQM 165
             |..|:|.     .|.:.|||.:.||          |:.:....|.          |::.|:..:
plant   108 VSEDGVIN-----ARARVLGGGSALNAGFYTRAGTKYVRNMGWDGA----------LANESYQWV 157

  Fly   166 RSFMAAAKPKNPDMLEIPRRYSKLTEALEEA----QAQFAYKDWI----FRRSLYNIRNGLRHSV 222
            .:.:|...|       :.|..:.:.:.|.||    ...|.| |.|    |..:::: |||.||:.
plant   158 EAKVAFQPP-------MGRWQTAVRDGLLEAGIVPNNGFTY-DHINGTKFGGTIFD-RNGNRHTA 213

  Fly   223 VQ--QFLNPVIHHSNLRLLPDALVKRIQLAPSPFLQATSILVGIKDEENRE-----KEFSIEVRR 280
            ..  ::.:|    ..:.:|..|.|.||........:..:..|..:|...:.     ||.::.
plant   214 ADLLEYADP----KGITVLLHATVHRILFRTRGTTKPIANGVVYRDRTGQAHRAYLKEGALS--- 271

  Fly   281 ELILCAGAYQTPQLLMASGIGDVSALKKLGIPAQHSLPLVGHNLHDH-FN-------LPLFVSM- 336
            |:||.||...:|||||.||:|..:.|:...|......|.||..::|: .|       :|:.||:
plant   272 EIILSAGTLGSPQLLMLSGVGPSAQLQAQNITVVMDQPHVGQGMYDNPMNAVFVPSPVPVEVSLI 336

  Fly   337 ---GVTGPTLNQNTLLNPMTLINYLSSGSGPLGNFGVLGNVVSYGGLGAPPYGITFFGAGAIDES 398
               |:||    :.|         |:.:..|.  |||. |...|.|......|...|.....:.||
plant   337 EVVGITG----EGT---------YVEAAGGE--NFGG-GGGGSSGSSSTRDYYAMFSPRATLLES 385

  Fly   399 ----ALMSISNFKGPAFRALFPRYYNSSQEGFVVISSCLQPKSRGSVGLLNRHMRRNPLIDPNYL 459
                .|.|...|:|                || ::...:.|.|.|.:.|..|:.:.||::..||.
plant   386 NSMTKLSSAQPFQG----------------GF-LLEKVMGPLSTGHLELKTRNPKDNPIVTFNYF 433

  Fly   460 SSEEDVACTISAIRSAVELVNSTAF-----------------AALHPRIHWPRVQECSNFGPFER 507
            ...:|:...:..|::...:|.|.||                 |:....:..||....::..|...
plant   434 QHPDDLKRCVRGIQTIERVVQSKAFSRYKYADVSFEYLLNLTASTPVNLRPPRSGPGASLPPSAE 498

  Fly   508 DFFDNRPSDQYLECLMRHVGLGSHHPGGTCALGSVVDSQLRLKGVSNVRVVDASVLPRPISGNPN 572
            :|           |  :|......|..|.|.:|.|||...::.|:..:||:|.|.:......||.
plant   499 EF-----------C--QHTVTTIWHYHGGCVVGRVVDGDYKVIGIDRLRVIDMSTVGYCPGTNPQ 550

  Fly   573 SVVVAIALRAASWILKSEL 591
            :.|:.:.......||:..|
plant   551 ATVMMLGRYMGVKILRERL 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaG	NP_650070.1	BetA	72..588	CDD:225186	135/574 (24%)
		NADB_Rossmann	119..327	CDD:304358	54/232 (23%)
		GMC_oxred_C	435..582	CDD:282984	37/163 (23%)
AT1G12570	NP_172718.2	PLN02785	10..572	CDD:215420	148/604 (25%)
		NADB_Rossmann	46..301	CDD:304358	77/288 (27%)
		NADB_Rossmann	47..>100	CDD:304358	21/55 (38%)
		GMC_oxred_C	409..557	CDD:282984	37/160 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I3423
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.780