Protein Alignment ninaG and Chdh

DIOPT Version :9

• Sequence 1: NP_650070.1
• Gene: ninaG / 41369
• FlyBaseID: FBgn0037896
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001129712.1
• Gene: Chdh / 218865
• MGIID: 1860776
• Length: 596
• Species: Mus musculus
• Alignment Length: 595
• Identity: 174/595 - (29%)
• Similarity: 256/595 - (43%)
• Gaps: 119/595 - (20%)

  Fly    47 FDYVIVGGGTGGSTLTSLLAKNSNGSVLLIEAG------GQFGLLSRIPLLTTFQQKGIND---W 102
            :.:|:||.|:.|..|.|.|.::.|..|||:|||      |...|..:|.:.........:|   |
Mouse    43 YTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYNW 107

  Fly   103 SFLSVPQKHSSRGLIERRQCLPRGKGLGGSANLNYMLHFDGHGPDFDSWRDHHNLSDWSWAQMRS 167
            .:.:.||.    |:..|....|||:..|||::||.|::..||..|::.|. ......|.:|....
Mouse   108 YYHTEPQP----GMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWH-REGAEGWDYAHCLP 167

  Fly   168 FMAAAK-------------------------PKNPDMLEIPRRYS-KLTEALEEAQAQ-FAYKDW 205
            :...|:                         |.:...|:..|:.. ..||.:...|.: |.:.|
Mouse   168 YFRKAQRHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMD- 231

  Fly   206 IFRRSLYNIRNGLRHSVVQQFLNPVIHHSNLRLLPDALVKRIQLAPSPFLQATSILVG---IKDE 267
                  ..:..|.|.|....:|:||:...|||.....||.|:      ..:.|. .||   |||.
Mouse   232 ------MTVHQGKRWSTACAYLHPVLSRPNLRAEVQTLVSRV------LFEGTR-AVGVEYIKDG 283

  Fly   268 ENREKEFSIEVRRELILCAGAYQTPQLLMASGIGDVSALKKLGIPAQHSLPLVGHNLHDHFNLPL 332
            : |.|.:   |.||:||..||..:|||||.||:|:...|:||.||....||.||.||.||  |.:
Mouse   284 Q-RHKAY---VSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDH--LEV 342

  Fly   333 FVSMGVTGP-TLN--QNTLLNPMTLINYLSS--GSGPLGNFGVLGNVVSYGGLGAPPYGITFFGA 392
            :|....|.| ||:  |..|......:.:|.|  |.|...:....|.:.|..|:..|.....|..:
Mouse   343 YVQQACTQPITLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPS 407

  Fly   393 GAIDESALMSISNFKGPAFRALFPRYYNSSQEGFVVISSCLQPKSRGSVGLLNRHMRRNPLIDPN 457
            ..||..        :.|           :.||.:.|....::..|.|.:.|.:.:.|.:|:|.||
Mouse   408 QVIDHG--------RKP-----------TQQEAYQVHVGTMRATSVGWLKLRSANPRDHPVIHPN 453

  Fly   458 YLSSEEDVACTISAIRSAVELVNSTAFA-----ALHPRIHWPRVQECSNFGPFERDFFDNRPSDQ 517
            |||:|.||......:|.:.|:....|.|     .|.|..|   ||                 ||:
Mouse   454 YLSTETDVEDFRQCVRLSREIFAQEALAPFRGKELQPGSH---VQ-----------------SDK 498

  Fly   518 YLECLMRHVGLGSHHPGGTCALG------SVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVV 576
            .::..:|.....::||..||.:|      :|||:|.::.||.|:||||||::|..:|||.|:..|
Mouse   499 EIDAFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTV 563

  Fly   577 AIALRAASWI 586
            .||.:||..|
Mouse   564 MIAEKAADII 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaG	NP_650070.1	BetA	72..588	CDD:225186	165/570 (29%)
		NADB_Rossmann	119..327	CDD:304358	71/237 (30%)
		GMC_oxred_C	435..582	CDD:282984	52/157 (33%)
Chdh	NP_001129712.1	PRK02106	42..588	CDD:235000	174/595 (29%)
		NAD_binding_8	47..>76	CDD:290186	13/28 (46%)
		GMC_oxred_N	118..341	CDD:279121	73/243 (30%)
		GMC_oxred_C	432..569	CDD:282984	52/156 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.700