Protein Alignment CG6723 and SLC5A2

DIOPT Version :9

• Sequence 1: NP_650069.2
• Gene: CG6723 / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_006721135.2
• Gene: SLC5A2 / 6524
• HGNCID: 11037
• Length: 705
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 118/509 - (23%)
• Similarity: 212/509 - (41%)
• Gaps: 77/509 - (15%)

  Fly    18 DYVAFVSMFLLCIGIGIYFGFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVY 82
            |.:...:.|||.||:|::........:...|.|.||.|:..|:..||.||.:.....:||.....
Human    32 DILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGA 96

  Fly    83 SYGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRF-DRRLRLYGSVMFAIMNV-AY 145
            :.|:.........:.:.:::|..:.||:....:.:..:||..|| .||:|||.||:...:.: ..
Human    97 ASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTK 161

  Fly   146 LPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISMLGALCLVAIKG 210
            :.:.::..|:...|..|..::.....:..|.:.||..|||.|:::||.||...:||..|::....
Human   162 ISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYA 226

  Fly   211 TRDIGGAGVVLERAWSSDRLEAPDLSI--DPTV------------------RHTF-----WCLFF 250
            ..::||...:.::...:    |..|::  ||.|                  ||..     |....
Human   227 FHEVGGYSGLFDKYLGA----ATSLTVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALL 287

  Fly   251 GGIV-----YWTQTNAVSQNMIQRYLSLPSLGDARKALCIFC----VGVLILMALCGYNGLLIY- 305
            .|:.     ||..    .|.::||.|:..||... ||.||.|    :..:.||.:.|....::|
Human   288 LGLTIVSGWYWCS----DQVIVQRCLAGKSLTHI-KAGCILCGYLKLTPMFLMVMPGMISRILYP 347

  Fly   306 ---------------ATYQNCDPLTTKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSS 355
                           .|...|..:.          .|..|:|.:..  |:.||.:|.:.:|.:||
Human   348 DEVACVVPEVCRRVCGTEVGCSNIA----------YPRLVVKLMPN--GLRGLMLAVMLAALMSS 400

  Fly   356 LSTCLNSMSAVVLEDFVKPYVKKPLSSSAINWIMRLVVVGVGVLCVCLVYVVE--HMGTVLQLTM 418
            |::..||.|.:...| :...::.......:..:.||.||.:.|:.|..:.||:  ..|.:.....
Human   401 LASIFNSSSTLFTMD-IYTRLRPRAGDRELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQ 464

  Fly   419 SLEAITNGPLFGIFTIGLFLPWINGNSALVGGVMGVIAMSWVSLNAQWAIASGA 472
            ::.:....|:..:|.:.||:|.:|...|. .|::|.:.|....|..:::..||:
Human   465 AVSSYLAPPVSAVFVLALFVPRVNEQGAF-WGLIGGLLMGLARLIPEFSFGSGS 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6723	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	118/509 (23%)
SLC5A2	XP_006721135.2	SLC5sbd_SGLT2	31..705	CDD:212056	118/509 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146478
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7765
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.690