Protein Alignment bumpel and Slc5a4b

DIOPT Version :10

• Sequence 1: NP_650069.2
• Gene: bumpel / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_075708.2
• Gene: Slc5a4b / 64454
• MGIID: 1890478
• Length: 660
• Species: Mus musculus
• Alignment Length: 494
• Identity: 122/494 - (24%)
• Similarity: 216/494 - (43%)
• Gaps: 50/494 - (10%)

  Fly    18 DYVAFVSMFLLCIGIGIYFGFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVY 82
            |....|..|::.:.:|::....:...:...:.|.|..|...|:..||.||.:.....:||.....
Mouse    28 DISVIVIYFIVVLAVGLWSMVRSNRGTVGGFFLAGHDMAWWPMGASLFASNIGSNHFVGLAGTGA 92

  Fly    83 SYGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRF-DRRLRLYGSVMFAIMNVA-Y 145
            :.||....|....:.|.:|:|..:||::....:.:..|||..|| .:||::|.||:...:.|| .
Mouse    93 ASGIAIAAVEWNALLMVLVLGWVFLPIYIKAGVLTMPEYLRKRFGGKRLQIYLSVLSLFIMVALQ 157

  Fly   146 LPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQA-ISMLGALCLVAIK 209
            ...:|:..|:......|:.::....|:..|..|||..|||.:|::||.||. |.:||:|.|:..
Mouse   158 TSSIIFSGAIFIQLALGLNLYLAVFILLAITAFYTVAGGLASVIYTDSVQTFIMLLGSLILMGF- 221

  Fly   210 GTRDIGGAGVVLERAWSS--DRLEAPDLSIDPTVR-------HTF---------W-CLFFG---- 251
            ...::||.....|:..::  ..:|..:|:|.|...       |.|         | .|.||
Mouse   222 AFAEVGGYESFTEKYMNAIPSVVEGDNLTISPKCYTPQPDSFHVFRDPVTGDIPWPGLIFGMTIL 286

  Fly   252 GIVYWTQTNAVSQNMIQRYLSLPSLGDARKALCIFCVGVL-----ILMALCGYNGLLIY------ 305
            .|.||    ...|.::||.|...::... ||.||.| |.|     .||.:.|....::|
Mouse   287 AIWYW----CADQVIVQRCLCGKNMSHV-KAACILC-GYLKLLPMFLMVMPGMISRILYTDKVAC 345

  Fly   306 ATYQNCDPLTTKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLED 370
            .....|:..........:...|..|::.:.:  |:.||.::.:.::.:|||::..||.|.:...|
Mouse   346 VVPSECEKQCGTAVGCTNYAYPTLVLELMPD--GLRGLMLSVMLASLMSSLTSIFNSASTLFTID 408

  Fly   371 FVKPYVKKPLSSSAI--NWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSLEAITNGPLFGIFT 433
            ......||......:  ..|..:|::.|.:|.|.||.|.:: |.:.....|:.:....||..:|.
Mouse   409 LYTKIRKKASERELMIAGRIFGMVLIAVSILWVPLVQVSQN-GQLFHYIGSVSSYLGPPLGAVFM 472

  Fly   434 IGLFLPWINGNSALVGGVMGVIAMSWVSLNAQWAIASGA 472
            :.:|...:|...|..|.::|:: :..:.|.|::...:|:
Mouse   473 LAIFFKRVNEQGAFWGLMVGLV-VGLIRLIAEFVYGTGS 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bumpel	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	122/494 (25%)
Slc5a4b	NP_075708.2	SLC5-6-like_sbd	27..660	CDD:444915	122/494 (25%)