Protein Alignment CG6723 and SLC5A7

DIOPT Version :9

• Sequence 1: NP_650069.2
• Gene: CG6723 / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001291934.1
• Gene: SLC5A7 / 60482
• HGNCID: 14025
• Length: 580
• Species: Homo sapiens
• Alignment Length: 603
• Identity: 140/603 - (23%)
• Similarity: 239/603 - (39%)
• Gaps: 102/603 - (16%)

  Fly    20 VAFVSMFLLCIGIGIYFGFMNK---SVSE--DDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPT 79
            :|.:..:||.:.:||:..:..|   |..|  :..::|||.:.::...|::.|::|.|..:.|...
Human     9 IAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAE 73

  Fly    80 EVY--SYGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRFDRRLRLYGSVMF--AI 140
            .||  .||:.:.....|.....::.|:|:..........:..:..:..:.:|:   |.::|  |:
Human    74 AVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRM---GGLLFIPAL 135

  Fly   141 MNVAYLPIVIYVPAL--AFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQA------- 196
            |...:....|: .||  ..:.:..:.:|....|..:|...||.:|||.:|.:|||||.
Human   136 MGEMFWAAAIF-SALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGL 199

  Fly   197 -ISMLGALCLVAIKGTRDIGGAGV--VLERAWSSDRLEAPDLSIDPTVRHTFWCLFFGGIVYWTQ 258
             ||:..||...|:   .|||...|  ..::.|    |...|.|...:...:|..|..|||.:
Human   200 WISVPFALSHPAV---ADIGFTAVHAKYQKPW----LGTVDSSEVYSWLDSFLLLMLGGIPW--- 254

  Fly   259 TNAVSQNMIQRYLSLPSLGDARKALCIFCVGVL------ILMALCGYNGLLIYATYQNCDPLTTK 317
                 |...||.||..|...|:....:...|.|      ||:...|.:.......|...||.||:
Human   255 -----QAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTE 314

  Fly   318 LAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAA-LSSLSTCLNSMSAVVLEDFVKPYVKKPLS 381
            .|   |.:||: |::.|  .|.....|..|..||| :||..:.:.|.|::...:..:...::..|
Human   315 EA---DMILPI-VLQYL--CPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNAS 373

  Fly   382 SSAINWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSLEAITNGPLFGIFTIGLFLPWINGNSA 446
            ...|.|:||:.|...|.....:..:.:.:..:..|:..|..|.   :|......||:...|...|
Human   374 DKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIV---IFPQLLCVLFVKGTNTYGA 435

  Fly   447 LVGGVMGVIAMSWVSLNAQWAIASGAITYKTKPLNVEQCDYSFNVTTSLANTTHLGASAED---- 507
            :.|.|.|:..          .|..|......:||                 ..:.|...:|
Human   436 VAGYVSGLFL----------RITGGEPYLYLQPL-----------------IFYPGYYPDDNGIY 473

  Fly   508 --IFPLYRISYMWYTTFGASITIFVALLGTFVFGKNN-PNKVDPVLLTPCIRKFFAFGSEKHMDA 569
              .||...::.:  |:|..:|.|  :.|..::|.... |.|:|      ......|..||::||
Human   474 NQKFPFKTLAMV--TSFLTNICI--SYLAKYLFESGTLPPKLD------VFDAVVARHSEENMD- 527

  Fly   570 FRPDIPLQHKLRNDEVAL 587
             :..:.....::.||:||
Human   528 -KTILVKNENIKLDELAL 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6723	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	127/550 (23%)
SLC5A7	NP_001291934.1	SLC5sbd_CHT	8..495	CDD:271368	126/544 (23%)
		Mediates interaction with SEC14L1. /evidence=ECO:0000250|UniProtKB:Q9JMD7	502..580		13/51 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740