DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6723 and slc5a8l

DIOPT Version :9

Sequence 1:	NP_650069.2	Gene:	CG6723 / 41368	FlyBaseID:	FBgn0037895	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001030141.1	Gene:	slc5a8l / 556156	ZFINID:	ZDB-GENE-061110-98	Length:	610	Species:	Danio rerio

Alignment Length:	579	Identity:	210/579 - (36%)
Similarity:	322/579 - (55%)	Gaps:	36/579 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GELQRFAWPDYVAFVSMFLLCIGIGIYFGFM-NKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGI 72
            |.:..|:..|||.|..:.|:..|||::..|. .|..|.|:::||||:|..:|:|.||.|||:|||
Zfish     6 GPVATFSVWDYVVFAGLILVAAGIGLFQSFRGRKEASSDEFLLGGRQMTAVPVALSLTASFMSGI 70

  Fly    73 TLLGLPTEVYSYGIQY--LYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRFDRRLRLYGS 135
            |::|.|.|.|.||..:  .::|..:  |..:....::|:|:.|||||||||||:|:::.:|:.|:
Zfish    71 TVIGTPAEAYLYGTPFWLFFISYAI--MSTISAEIFVPLFYRLNITSTYEYLEMRYNKLIRVIGT 133

  Fly   136 VMFAIMNVAYLPIVIYVPALAFNQVTGI---GVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAI 197
            .|:.|....|..:||:.||||.||:||:   ||...|..||||   |.:|||||||:||||.|.|
Zfish   134 SMYIIQTALYTGMVIFAPALALNQITGLDLWGVLVATGAVCII---YCTLGGLKAVIWTDVFQMI 195

  Fly   198 SMLGALCLVAIKGTRDIGGAGVVLERAWSSDRLEAPDLSIDPTVRHTFWCLFFGGIVYWTQTNAV 262
            .|||....|..:|....||.|.|...::...|||......||..||:||.:..||.:.|....::
Zfish   196 IMLGGFVAVIARGAVLQGGLGRVWNDSFYGGRLETFSFDPDPLRRHSFWTIVVGGSLMWASMYSI 260

  Fly   263 SQNMIQRYLSLPSLGDARKALCIFCVGVLILMALCGYNGLLIYATYQNCDPLTTKLAKARDQLLP 327
            :|:.:|||:|..::..|:.:|.:..||:.:.::|...:||.:|:.|::|||.|.|...|.|||||
Zfish   261 NQSQVQRYISCRTMTHAKLSLYVNMVGLWVTVSLAMMSGLTMYSIYKDCDPFTNKDVGATDQLLP 325

  Fly   328 LFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFVKPYVKKPLSSSAINWIMRLV 392
            ..||..|.:.||:.|||:|..:|..||::|:.:|::.||.:|||:|| ....|:...::||...:
Zfish   326 YLVMDILADFPGLPGLFVAAAYSGTLSTVSSSINALVAVTVEDFMKP-AWPSLTERQLSWINMGM 389

  Fly   393 VVGVGVLCVCLVYVVEHMGTVLQLTMSLEAITNGPLFGIFTIGLFLPWINGNSALVGGVMGVIAM 457
            .|..|.:|:.:..|...||.:||..:|:..:.:|||.|::.:|:|....|....|.|...|:...
Zfish   390 SVFYGAVCIGMAGVASMMGNILQAALSIFGMISGPLLGLYMLGMFFRCANSTGGLAGLASGLAIT 454

  Fly   458 SWVSLNAQWAIASGAITYKT--KPLNVEQCDYSFN---VTTSLANTTHLGASAEDIFPL-----Y 512
            .||.:.||   ....:..||  .||:||.| .:.|   .||....:|.|..:.....|.     |
Zfish   455 LWVGIGAQ---LYPPLPEKTLRLPLSVEGC-VALNTSETTTMTPFSTVLQTTTPQPRPALADNWY 515

  Fly   513 RISYMWYTTFGASITIFVALLGTFVFGKNNPNKVDPVLLTPCIRKFFAFGSEKHMDAFR 571
            .:||::::..|..:|:.:||:.:.:.|.....||.|.|          |.|:..:..||
Zfish   516 SLSYLYFSPVGIVVTMIIALIVSAISGGCKQKKVRPEL----------FISKSDLICFR 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6723	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	199/535 (37%)
slc5a8l	NP_001030141.1	SLC5sbd_SMCT1	8..547	CDD:271402	201/548 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580108
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.940