Protein Alignment bumpel and Slc5a3

DIOPT Version :10

• Sequence 1: NP_650069.2
• Gene: bumpel / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_059087.2
• Gene: Slc5a3 / 53881
• MGIID: 1858226
• Length: 718
• Species: Mus musculus
• Alignment Length: 563
• Identity: 130/563 - (23%)
• Similarity: 237/563 - (42%)
• Gaps: 89/563 - (15%)

  Fly    20 VAFVSM-FLLCIGIGIYFGFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVYS 83
            :|.|:: |:|.:.||.:..:.:...:...|.|.||.|..:.|..||..|.:.....:||.....:
Mouse    10 IAVVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAA 74

  Fly    84 YGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRF-DRRLRLYGSVMFAIMNV-AYL 146
            .|..........:.:..::|..::|::....:.:..|||..|| ..|:::|.:.:..::.: ..|
Mouse    75 SGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLLLYIFTKL 139

  Fly   147 PIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISM-LGALCLVAIKG 210
            .:.:|..||...:..|..::....::..:....|..|||.||::||.:||:.| :|||.|:.|..
Mouse   140 SVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISM 204

  Fly   211 TRDIGGAGVVLERAWSSDRLEAPDLSI--------------------------DPTVRHTFWCLF 249
            .: |||...|..|.    .|.:||::.                          |||.....|..|
Mouse   205 VK-IGGFEEVKRRY----MLASPDVASILLKYNLSNTNACMVHPKANALKMLRDPTDEDVPWPGF 264

  Fly   250 FGG-----IVYWTQTNAVSQNMIQRYLSLPSLGDAR---------KALCIFCVGVLILMALCGYN 300
            ..|     :.||    ...|.::||.|:..::..|:         |.|.:|.:.|..:::...:.
Mouse   265 ILGQTPASVWYW----CADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRIVFA 325

  Fly   301 GLLIYATYQNCDPLTTKLAKARDQLLPLFVMKTLGELP-GMTGLFIAGVFSAALSSLSTCLNSMS 364
            ..:.....::|..:....|...:...|..|| ||  :| |:.||.:|.:.:|.:|.|.:..||.|
Mouse   326 DEIACINPEHCMQVCGSRAGCSNIAYPRLVM-TL--VPVGLRGLMMAVMIAALMSDLDSIFNSAS 387

  Fly   365 AVVLEDFVKPYVKKPLSSSAINWIMRLVVVGVGVLCVCLV-YVVEHMGTVLQLTMSLEAITN--- 425
            .:...|..| .::|..||..:..:.|:.|..:.|:.:..| .:||..|.  |:.:.::.:.:
Mouse   388 TIFTLDVYK-LIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGG--QMYLYIQEVADYLT 449

  Fly   426 GPLFGIFTIGLFLPWINGNSALVGGVMGVIAMSWVSLNAQWAIASGAITYKTKPLNVEQCDYSFN 490
            .|:..:|.:.:|....|...|..||:.|.:      |.|...|.  |.||:     ..:||...|
Mouse   450 PPVAALFLLAIFWKRCNEQGAFYGGMAGFV------LGAVRLIL--AFTYR-----APECDQPDN 501

  Fly   491 VTTSLANTTHLGASAEDIFPLYRISYMWYTTFGASITIFVALL 533
            ....:          :||..:|..:.:::.|  ..||:.|:||
Mouse   502 RPGFI----------KDIHYMYVATALFWIT--GLITVIVSLL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bumpel	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	130/563 (23%)
Slc5a3	NP_059087.2	SLC5sbd_SMIT	9..718	CDD:271382	130/563 (23%)