DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6723 and CG31668

DIOPT Version :9

Sequence 1:	NP_650069.2	Gene:	CG6723 / 41368	FlyBaseID:	FBgn0037895	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001097055.2	Gene:	CG31668 / 33395	FlyBaseID:	FBgn0051668	Length:	590	Species:	Drosophila melanogaster

Alignment Length:	572	Identity:	220/572 - (38%)
Similarity:	327/572 - (57%)	Gaps:	35/572 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RFAWPDYVAFVSMFLLCIGIGIYFGFMNKS---------VSE--------------DDYMLGGRK 54
            ||...||..|:.:.:|.|.||:||||:.||         .:|              :|||:|.|.
  Fly     5 RFGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRN 69

  Fly    55 MLVIPIAFSLVASFVSGITLLGLPTEVYSYGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTY 119
            :.|.|:..||:||.:|.:.::|.|:|:|:||.||.::...::..|:.:...|||||..|.:||:|
  Fly    70 LRVFPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQVTSSY 134

  Fly   120 EYLEVRFDRRLRLYGSVMFAIMNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGG 184
            ||||:||...:|...|::|.:..|.|||.:.|:||||.|||:|:.::.|...:.:|||.||.|||
  Fly   135 EYLEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGG 199

  Fly   185 LKAVVWTDVVQAISMLGALCLVAIKGTRDIGGAGVVLERAWSSDRLEAPDLSIDPTVRHTFWCLF 249
            |||||.||:.|.:.|..::..:.:..|..|......||......||...:.:..|..|||.|.:.
  Fly   200 LKAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLEGLVRGGRLIFSETNPSPFARHTVWSVV 264

  Fly   250 FGGIVYWTQTNAVSQNMIQRYLSLPSLGDARKALCIFCVGVLILMALCGYNGLLIYATYQNCDPL 314
            .|...|||..|||.|.::.||:|||:|..||.::....||....::|..|.||||:..|::||||
  Fly   265 IGNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIFHAYRDCDPL 329

  Fly   315 TTKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFVKPYVKKP 379
            :..|....|||:||||:.:||.:.||.||||||:|.|:|||||..|||.|.|:|:|.|:...|..
  Fly   330 SAGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCFKME 394

  Fly   380 LSSSAINWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSLEAITNGPLFGIFTIGLFLPWINGN 444
            |...|...:::..:|.:|:|...:|:|:|.:..||.:::||.||.....|||||:|:.:||.|..
  Fly   395 LGEWASTIVVKGSIVVLGLLAFAMVFVLEKVSGVLSISVSLAAIAASSTFGIFTVGMLVPWANTV 459

  Fly   445 SALVGGVMGVIAMSWVSLNAQWAIASGAITYKTKPLNVEQCDYSFNVTTSLANTT---HLGASAE 506
            ...|||:..|:...|:|..:|:|.|||.:..:..|::||.|         |||.:   :...:.|
  Fly   460 GTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGC---------LANASVAENAWVAEE 515

  Fly   507 DIFPLYRISYMWYTTFGASITIFVALLGTFVFGKNNPNKVDPVLLTPCIRKF 558
            ::|||||:||.|.:..|....:.|..|.:.|....:...:|..|:||.|.:|
  Fly   516 EVFPLYRLSYHWISPIGVLTVVVVGSLVSLVTKPTDIKSLDSDLITPVIHRF 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6723	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	211/545 (39%)
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	208/530 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448250
Domainoid	1	1.000	233	1.000	Domainoid score	I1353
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1946
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D32058at33392
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900