Protein Alignment bumpel and Slc5a11

DIOPT Version :10

• Sequence 1: NP_650069.2
• Gene: bumpel / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001093952.2
• Gene: Slc5a11 / 252854
• RGDID: 621410
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 116/490 - (23%)
• Similarity: 197/490 - (40%)
• Gaps: 80/490 - (16%)

  Fly    18 DYVAFVSMFLLCIGIGIYFGFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVY 82
            |.|..|..||..:.:|::.....|..:...|.|.|..|:..|:..||.||.|.....:||.....
  Rat    28 DIVVLVLYFLFVLAVGLWSTVRTKRDTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGA 92

  Fly    83 SYGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRFDRRLRLYGSVMFAIMNVAYLP 147
            :.||.........:...:::...:||::....:|:..|||..||.      ||.:...:.|.||.
  Rat    93 AVGISVAAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLRRRFG------GSRIPITLAVLYLF 151

  Fly   148 IVI--------YVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISML-GAL 203
            |.|        |..|:...|...:.::.....:..:...||..|||.||::||.:|.:.|| ||.
  Rat   152 IYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAVTALYTVAGGLAAVIYTDALQTVIMLIGAF 216

  Fly   204 CLV--------AIKGTRDIGGAGVVLERAWSSD----RLEAPDLSIDPTVRHTFW-CLFFG---- 251
            .|:        .::|.:|.....:...|:.:|.    |.:|..:..||......| .:.||
  Rat   217 ILMGYSFAAVGGMEGLKDQYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPWPGILFGMSIP 281

  Fly   252 GIVYWTQTNAVSQNMIQRYLSLPSLGDAR---------KALCIFCVGVLILMALCGYNGLLIY-- 305
            .:.||    ...|.::||.|:..:|..|:         |.|.:|      ||...|....:::
  Rat   282 SLWYW----CTDQVIVQRSLAAKNLSHAKGGSLMAAYLKVLPLF------LMVFPGMVSRILFPD 336

  Fly   306 ----ATYQNCDPLTTKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAV 366
                |....|..:.:..:...|...|..|::.|.  .|:.||.:|.:.:|.:|||::..||.|.:
  Rat   337 QVACAHPDICQRVCSNPSGCSDIAYPKLVLELLP--TGLRGLMMAVMVAALMSSLTSIFNSASTI 399

  Fly   367 VLEDF---VKPYVKKPLSSSAINWIMRLVVVG-VGVLCVCLVYVV-------EHMGTVLQLTMSL 420
            ...|.   ::|...:          ..|::|| |.||.:.||.::       ...|.:.....|:
  Rat   400 FTMDLWHHIRPRASE----------RELMIVGRVFVLALVLVSILWIPVVQASQGGQLFIYIQSI 454

  Fly   421 EAITNGPLFGIFTIGLFLPWINGNSALVGGVMGVI 455
            .:....|:..:|.:|.|....|...|..|.::|::
  Rat   455 SSYLQPPVAVVFIMGCFWKRTNEKGAFSGLILGLL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bumpel	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	116/490 (24%)
Slc5a11	NP_001093952.2	SLC5-6-like_sbd	28..673	CDD:444915	116/490 (24%)