DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6723 and Slc5a9

DIOPT Version :9

Sequence 1:	NP_650069.2	Gene:	CG6723 / 41368	FlyBaseID:	FBgn0037895	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_663526.3	Gene:	Slc5a9 / 230612	MGIID:	2140201	Length:	685	Species:	Mus musculus

Alignment Length:	481	Identity:	118/481 - (24%)
Similarity:	215/481 - (44%)	Gaps:	54/481 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DYVAFVSMFLLCIGIGIYFGFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVY 82
            |.|..|..|:..:.:||:........:...|.|.||.|...||..||::|.|.....:||.....
Mouse    33 DIVVVVIYFVFVLAVGIWSSIRASRGTVGGYFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGA 97

  Fly    83 SYGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRF-DRRLRLYGSVMFAIMNV-AY 145
            :.|:...........:.:.:|..::||:....:.:..:||:.|| .:|:::|.||:..|:.: ..
Mouse    98 AGGLAVGGFEWNATFLLLALGWIFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTK 162

  Fly   146 LPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISMLGALCLVAIKG 210
            :...|:..||......|..::..|.|:.::...||..|||.||::||.:|.:.|:|...::...|
Mouse   163 ISTDIFSGALFIQMALGWNLYLSTVILLVVTAVYTIAGGLTAVIYTDALQTVIMVGGALVLMFLG 227

  Fly   211 TRDIG---GAGVVLERAW-------SSDRLEAPD---LSIDPTVRHTFW-CLFFGGIVYWTQTNA 261
            .:::|   |...:..:|.       ::..|..||   :..||......| .|.||..|..|....
Mouse   228 FQEVGWYPGLQQLYRQAIPNTTVPNTTCHLPRPDAFHMLRDPVNGDIPWPGLIFGLTVLATWCWC 292

  Fly   262 VSQNMIQRYLSLPSLGDAR---------KALCIFCVGVLILMALCGYNGLLIYATYQN---C-DP 313
            ..|.::||.|:..:|..|:         |.|.:|    .|:|.     |::..|.|.:   | ||
Mouse   293 TDQVIVQRSLAAKNLSHAKGGSVLGGYLKILPMF----FIVMP-----GMISRALYPDEVACVDP 348

  Fly   314 -LTTKLAKAR----DQLLPLFVMKTLGELP-GMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFV 372
             :..::..||    :...|..||..   :| |:.||.||.:.:|.:|||::..||.|.:...|..
Mouse   349 DICQRVCGARVGCSNIAYPKLVMAL---MPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFAIDVW 410

  Fly   373 KPYVKKPLSSSAINWIMRLVVVGVGVLCVCLVYVVE--HMGTVLQLTMSLEAITNGPLFGIFTIG 435
            :.: ::..|...:..:.||.||.:.|:.:..:.:::  :.|.:.....|:.:....|:..:|.:.
Mouse   411 QRF-RRQASEQELMVVGRLFVVFLVVISILWIPIIQSSNSGQLFDYIQSITSYLAPPITALFLLA 474

  Fly   436 LFLPWINGNSA----LVGGVMGVIAM 457
            :|...:|...|    :.|.|:|::.|
Mouse   475 IFCKRVNEPGAFWGLMFGLVVGILRM 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6723	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	118/481 (25%)
Slc5a9	NP_663526.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SLC5-6-like_sbd	45..685	CDD:382020	114/469 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	577..616
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836516
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740