Protein Alignment bumpel and smvt-1

DIOPT Version :10

• Sequence 1: NP_650069.2
• Gene: bumpel / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001360058.2
• Gene: smvt-1 / 186132
• WormBaseID: WBGene00018716
• Length: 565
• Species: Caenorhabditis elegans
• Alignment Length: 598
• Identity: 168/598 - (28%)
• Similarity: 295/598 - (49%)
• Gaps: 63/598 - (10%)

  Fly    18 DYVAFVSMFLLCIGIGIYFGFMNKSVSEDD------YMLGGRKMLVIPIAFSLVASFVSGITLLG 76
            ::..:|::....|.|..| ||:....:|::      .|:|.| :.|.....|:.:.|:|.|:|||
 Worm     2 EFSDYVTLLTCLISISAY-GFIKSRKTENEEQSVHATMVGSR-VSVWSATLSVCSGFISSISLLG 64

  Fly    77 LPTEVYSYGIQYL-YVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRFDRRLRLYGSVMFAI 140
            .|.|:|..|...| :....||...:|..|| |||.:.|.:|:.|||.|.|||.:.|...:.:|.:
 Worm    65 FPAEIYYQGGMMLWFAPMYVISFPIVAFVF-LPVLYRLKLTTIYEYFERRFDYKCRFVTTSLFCV 128

  Fly   141 MNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISMLGALCL 205
            ..:.|..:.:|.|:||...:|.|.:.....|..::..||.|:||:||.:.|..:|.:.:...:..
 Worm   129 QMILYNSVALYAPSLAIASITNIPITVSILITAVLSAFYISVGGVKAGIHTSAIQMLLIFLTMTF 193

  Fly   206 VAIKGTRDIGGAGVVLERAWSS----DRLEAPDLSIDPTVRHTFWCLFFGGIVYWTQTNAVSQNM 266
            :.....|::.     :...::|    .|....|..|:||:||:.|.|..||........|.:|..
 Worm   194 IISISLREMS-----IHDVYTSVVHGKRFILNDFRINPTIRHSVWSLLIGGTGNILALFAANQLS 253

  Fly   267 IQRYLSLPSLGDARKA--LCIFCVGVLILMALCGYNGLLIYATYQNCDPLTTKLAKARDQLLPLF 329
            ||||:::.:|..|:|.  |.|.| ..:||::.... |.||||.|::|.|   ::..| ::|||.|
 Worm   254 IQRYMAMDTLKSAQKVVLLNIVC-NTIILVSYVSV-GFLIYAHYKDCHP---QIGNA-NELLPRF 312

  Fly   330 VMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFVKPYVKK----PLSSSAINWIMR 390
            ||....:.||..|||.|.|:||.:|:||....::|::|:.|..|.|.::    ||.:..:...||
 Worm   313 VMDVTSKYPGSVGLFAAAVYSAGISTLSASFTAVSSIVINDVWKVYRERRKMAPLRNDQVQNAMR 377

  Fly   391 LVVVGVGVLCVCLVYVVEHM-GTVLQLTMSLEAITNGPLFGIFTIGLFLPWINGNSALVGGVMGV 454
            ::.:.:..:.:.:.::...: ..:||::..:.....||:.|.|.:|||:|.:...:||||.:..:
 Worm   378 ILPIVLSFISIFVAFLCSMLQSIILQVSFIVFGAGGGPVLGSFVVGLFVPRVKEKAALVGLIGSI 442

  Fly   455 IAMSWVSLNAQWAIASGAITYKTKPLNVE--QCDYSFNVTTSLANTTHLGA--SAEDIFPLYR-- 513
            |..        ::|:.|::..|.||:.:|  ||.   |.|.:..:.:.:||  |...:|.|.|
 Worm   443 IVC--------FSISIGSVLVKVKPVALELGQCS---NQTLTYFDESFIGAVTSTPLVFGLERIF 496

  Fly   514 -ISYMWYTTFGASITIFVALLGTFVFG----KNNPNKVDPVLLTPCIRKFFAFGSEKHMDAFRPD 573
             |||.:|:.......:.::::...:|.    ..|...|...|::|.:    .:.|.|.    .|:
 Worm   497 AISYQYYSIIAVVTNVALSIVMQKLFELCSLTANHLPVSHELVSPLL----TYSSSKR----DPE 553

  Fly   574 IPLQHKLRNDEVA 586
            :. .|:.:.|.:|
 Worm   554 LE-AHRTQRDTLA 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bumpel	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	157/543 (29%)
smvt-1	NP_001360058.2	SLC5sbd_NIS-SMVT	5..521	CDD:271383	157/540 (29%)