Protein Alignment bumpel and Slc5a6

DIOPT Version :10

• Sequence 1: NP_650069.2
• Gene: bumpel / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_570102.1
• Gene: Slc5a6 / 170551
• RGDID: 69648
• Length: 634
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 195/585 - (33%)
• Similarity: 313/585 - (53%)
• Gaps: 33/585 - (5%)

  Fly    11 LQRFAWPDYVAFVSMFLLCIGIGIYF---GFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGI 72
            :..|:..|||.|..:.:|.:.||:|.   |:...:|.|  .::..|||..:|:|.||:|:|.|.:
  Rat    20 ISTFSVVDYVVFGLLLVLSLVIGLYHACRGWGRHTVGE--LLMADRKMGCLPVALSLLATFQSAV 82

  Fly    73 TLLGLPTEVYSYGIQYLYVSCG-VIGMGVVMGVFYLPVFHDLNITSTYEYLEVRFDRRLRLYGSV 136
            .:||.|.|:|.:|.||.::.|. .:|:.:...:| :|||:.|::||.|||||:||::.:|:.|:|
  Rat    83 AILGGPAEIYRFGTQYWFLGCSYFLGLLIPAHIF-IPVFYRLHLTSAYEYLELRFNKAVRICGTV 146

  Fly   137 MFAIMNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISMLG 201
            .|....|.|:.:.:|.|:||.|.|||..:......:.|:|..||:|||||||:||||.|.:.|..
  Rat   147 TFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKAVIWTDVFQTLIMFL 211

  Fly   202 ALCLVAIKGTRDIGGAGVVLERAWSSDRLEAPDLSIDPTVRHTFWCLFFGGIVYWTQTNAVSQNM 266
            ...:|.|.|...:||.|.|...|.....:...:|..||.||||||.|.|||:........|:|..
  Rat   212 GQLVVIIVGAAKVGGLGHVWAVASQHGLISGIELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQ 276

  Fly   267 IQRYLSLPSLGDARKALCIFCVGVL----ILMALCGYNGLLIYATYQNCDPLTTKLAKARDQLLP 327
            :|||||    ..:.||..:.|..|.    :.:.:....||:::|.|:.......:...|.|||:.
  Rat   277 VQRYLS----SHSEKAAVLSCYAVFPCQQVALCMSCLIGLVMFAYYKKYSMSPQQEQAAPDQLVL 337

  Fly   328 LFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFVKPYVKKPLSSSAINWIMRLV 392
            .|||..|.::||:.|||:|.:||.:||::|:..||::.|.:||.::|:..:...:.|| .:.|.:
  Rat   338 YFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQPWFPQLTETRAI-MLSRSL 401

  Fly   393 VVGVGVLCVCLVYVVEHMGTVLQLTMSLEAITNGPLFGIFTIGLFLPWINGNSALVGGVMGVIAM 457
            ....|::|:.:.||..|:|:|||..:|:..:..|||.|:|.:|:|.|..|...|:||.:.|:...
  Rat   402 AFAYGLVCLGMAYVSSHLGSVLQAALSIFGMVGGPLLGLFCLGMFFPCANPLGAIVGLLTGLTMA 466

  Fly   458 SWVSLNAQWAIASGAITYKTKPLNVEQCDYSFNVTTSLANTTHLGASA----EDIFPLYRISYMW 518
            .|:.:.:..:..|.|..  :.|||........|:|  :|..|.|..|.    ..:...|.:||:|
  Rat   467 FWIGIGSIVSRMSSAAA--SPPLNGSSSFLPSNLT--VATVTTLMPSTLSKPTGLQQFYSLSYLW 527

  Fly   519 YTTFGASITIFVALLGTFVFG-----KNNPNKVDPVLLTPCIRKFFAFGSEKHM--DAFRPDIPL 576
            |:...::..|.|.|:.:.:.|     ..||..:.|||  |.:........:|.:  .:...|||:
  Rat   528 YSAHNSTTVIAVGLIVSLLTGGMRGRSLNPGTIYPVL--PKLLALLPLSCQKRLCWRSHNQDIPV 590

  Fly   577  576
              Rat   591  590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bumpel	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	183/531 (34%)
Slc5a6	NP_570102.1	SLC5-6-like_sbd	23..548	CDD:444915	184/536 (34%)