Protein Alignment bumpel and Slc5a10

DIOPT Version :10

• Sequence 1: NP_650069.2
• Gene: bumpel / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_006532041.1
• Gene: Slc5a10 / 109342
• MGIID: 1926089
• Length: 611
• Species: Mus musculus
• Alignment Length: 486
• Identity: 119/486 - (24%)
• Similarity: 200/486 - (41%)
• Gaps: 92/486 - (18%)

  Fly    18 DYVAFVSMFLLCIGIGIYFGFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVY 82
            |.:.....|.|.:.:||:........:...|.|.||.|...||..||.||.......:||
Mouse    55 DIIVISVYFALNVAVGIWSACRANKNTVSGYFLAGRDMAWWPIGASLFASSEGSGLFVGL----- 114

  Fly    83 SYGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRF-DRRLRLYGSVMFAIMNV-AY 145
                    ...|..| |:.:..|      :.||.:..||::.|| .:|:|.|.||:..:::| ..
Mouse   115 --------AGSGAAG-GLAVAGF------EWNIVTLPEYIQKRFGGQRIRTYLSVLSLMLSVFTK 164

  Fly   146 LPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISMLGALCLVAIKG 210
            :.|.:|..||..:...|...:..|.:...|...||..|||..|::||.:|.|.|:....::|:|.
Mouse   165 ISIDLYAGALFVHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDALQTIIMVVGAVILAVKA 229

  Fly   211 TRDIGGAGVVLERAWSS--------------DRLEAPDLSIDPTVRHTFWC-LFFGGIV----YW 256
            ...|||. ..||.|::.              .|.:|..:..||:.....|. :.||..:    ||
Mouse   230 FNQIGGY-EQLEAAYAQAIPSRTIPNTTCHLPRADAMHMFRDPSTGDLPWTGMTFGLTIMATWYW 293

  Fly   257 TQTNAVSQNMIQRYLSLPSLGDARKALCIFCVGVLILMALCGYNGLLIYATYQN----------- 310
                ...|.::||.||..:|..|:....:.....::.|.|....|::....:.:
Mouse   294 ----CTDQVIVQRSLSARNLNHAKAGSILASYLKMLPMGLMIMPGMISRVLFPDDVGCVVPSECL 354

  Fly   311 --------CDPLT-TKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAV 366
                    |..:. .||..   :|:|:          |:.||.||.:.:|.||||::..||.|.:
Mouse   355 RACGAEIGCSNIAYPKLVM---ELMPI----------GLRGLMIAVMMAALLSSLTSIFNSSSTL 406

  Fly   367 VLEDFVKPYVKKPLSSSA----INWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSLEAITNG- 426
            ...|     :.:.|..||    :..:.|||:|.:..:.|..:.|::...:. ||.:.::::|:.
Mouse   407 FTMD-----IWRQLRPSAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSG-QLFIYMQSVTSSL 465

  Fly   427 --PLFGIFTIGLFLPWINGNSALVGGVMGVI 455
              |:..||.:|:|....|...|..|.:.|::
Mouse   466 APPVTAIFILGIFWRRANEQGAFWGLMAGLV 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bumpel	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	119/486 (24%)
Slc5a10	XP_006532041.1	SLC5-6-like_sbd	52..611	CDD:444915	119/486 (24%)