DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ranbp9 and TRN1

DIOPT Version :9

Sequence 1:	NP_001287284.1	Gene:	Ranbp9 / 41367	FlyBaseID:	FBgn0037894	Length:	1018	Species:	Drosophila melanogaster
Sequence 2:	NP_179287.3	Gene:	TRN1 / 816198	AraportID:	AT2G16950	Length:	895	Species:	Arabidopsis thaliana

Alignment Length:	960	Identity:	180/960 - (18%)
Similarity:	327/960 - (34%)	Gaps:	272/960 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IEELQNLLS---SDTGVLQQTE--KRIKQLEYTEGYGVYLSEIIMN-QAHELPLRQIAIVMLTRY 76
            :.|:.:||.   |.:.|:.:::  |:::.......:..||..|::. :...:.:||.|.::|...
plant    15 LAEICSLLEQQISPSSVVDKSQIWKQLQHFSQFPDFNNYLVFILVRAEGKSVEVRQAAGLLLKNN 79

  Fly    77 VENHWTDDDDVKRKANGCMASEQAKRTIRNILP-NGLYDPNSKIRSSVAHTISTIAATDYPHCWA 140
            :           |.|...|..|..|.....:|| .|..|.|  ||::|...||.|...:....|.
plant    80 L-----------RGAYPSMTQENQKYIKSELLPCLGAADRN--IRTTVGTIISVIVNIEGVSGWH 131

  Fly   141 ELFDIIVKCLGGNE-DSIHGAMQVLQDFSYDVEQIKELG---------PVVIPEVYRIFDSEQNY 195
            ||...:|.||..|: :.:.|||..|.....|:..:.:..         .:.:|.:.:.|.|....
plant   132 ELLPALVTCLDSNDLNHMDGAMDALSKICEDIPHVLDTEVPGLAERPINIFLPRLLQFFQSPHAS 196

  Fly   196 SIKTRVSAIR---ILKPLFASIAALITNKEEQSTMMSSILTNFMDKLMHYLSMNSGAVSSFLL-- 255
            ..|..:.::.   |:.|                .::...|.|.:||.:..|         |:|
plant   197 LRKLALGSVNQYIIIMP----------------AVIWQALYNSLDKYLQGL---------FVLAN 236

  Fly   256 ------RTEIIKVFTHLVNEMPKYINPFMDRVLPIVWQLLTQIAETYVKVSVNQTETSPLASGDS 314
                  |..:...|.||...:|..|.|.:..|:..:.|:                         :
plant   237 DPVPEVRKLVCAAFVHLTEVLPSSIEPHLRNVMEYMLQV-------------------------N 276

  Fly   315 EEDDEQTNFQSLIIQILEFINCILTCNKLRGSIKNVLADLIYITIVYIQLS--EEQLEDWHDD-- 375
            .:.||:.:     ::..||.:..........::|..|..||.:.:..:..:  :|.|.|..:|
plant   277 RDPDEEVS-----LEACEFWSAYCDAQLPPENLKEFLPRLIPVLLENMAYADDDESLLDAEEDES 336

  Fly   376 -------------------PEKFVDDEDDGGVELTVRMCGRDVLLAINDEFGANAIQPLQEALGR 421
                               .|.|.||:||......:|.|....:..:::.||...:..|...:.:
plant   337 QPDRDQDLKPRFHTSRLHGSEDFDDDDDDSFNVWNLRKCSAAAIDVLSNVFGDEILPALMPLIQK 401

  Fly   422 HFSVADAEKAANNPNWWKIQEACMDAVHAFRDVILAGDSTFDLLNYLT-IVRNL--LVHQESPPL 483
            :.|.:..|.       ||.:||.:.|:.|..:..:.|     |..:|: ||..|  |:..:.|.:
plant   402 NLSASGDEA-------WKQREAAVLALGAIAEGCMNG-----LYPHLSEIVAFLLPLLDDKFPLI 454

  Fly   484 VGRALWTLSIYSK---SDLYNPQ-----------MLTEILDV------TLCSLSPEKSHILRISA 528
            ...:.||||.:.|   .:..||:           :|..:||.      ..||.............
plant   455 RSISCWTLSRFGKYLIQESGNPKGYEQFEKVLMGLLRRLLDTNKRVQEAACSAFATVEEDAAEEL 519

  Fly   529 VRTLNGFLQANETIDG--EKRTLLVSKLPGFLDGIMALVPG-----SKAAVLALLMEALTF---- 582
            |..|...||......|  ::|.|.:     ..|.|..|...     :|.|.|.:||..|..
plant   520 VPHLGVILQHLMCAFGKYQRRNLRI-----VYDAIGTLADSVREELNKPAYLEILMPPLVAKWQQ 579

  Fly   583 MVKFDAE-------FAFASQA---KITPLAIAVFLKYTEDPYVLETVQDLIKALCQRKECLGPLQ 637
            :...|.:       |...|||   ...|.|..||                       :.|:..:|
plant   580 LSNSDKDLFPLLECFTSISQALGVGFAPFAQPVF-----------------------QRCMDIIQ 621

  Fly   638 EKFIPTIVSILGLTGAASTEKQDI--ALDVLNTIVRYTEPPLNNSLLETAF-PAIINCVLHTDDH 699
               :..:..:...:..|..:::.|  :||:|:.:.......:.:.:.::.. ..::||.:   |.
plant   622 ---LQQLAKVNPASAGAQYDREFIVCSLDLLSGLAEGLGSGIESLVQQSNLRDLLLNCCI---DE 680

  Fly   700 AVMVAG------GECLR-----------SFINVSPEQICSYKNGEGINCIMQVVATVLLNPMNSE 747
            |..|..      |:..|           .|:.::.:|:.:..|.|.            |:..|:.
plant   681 AADVRQSAFALMGDLARVFPVYLQPRLLDFLEIASQQLSANLNREN------------LSVANNA 733

  Fly   748 MTAAGQIG----RLVITIITKMGSMLG---QNVDMLLKAVISKMQNLECLKVIMNLVLIFAHLFL 805
            ..|.|::.    :.|..|:.|:.|.||   |:.:.:.||::.            |..:....|..
plant   734 CWAIGELAVKVRQEVSPIVAKVVSSLGLILQHGEGVNKALVE------------NSAITLGRLAW 786

  Fly   806 TQMDAVLNFLSTVPGPNGEPAMQFVLTNWLSRQNSFFGNYERKVTTMALC 855
            .:.|.|            .|.|...:..|....:....:.|::.....||
plant   787 IRPDLV------------APHMDHFMKPWCMALSMVRDDIEKEDAFRGLC 824

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ranbp9	NP_001287284.1	SXM1	14..891	CDD:227943	180/960 (19%)
Ranbp9	NP_001287284.1	IBN_N	36..114	CDD:281761	16/81 (20%)
TRN1	NP_179287.3	IBN_N	38..104	CDD:281761	15/76 (20%)
		HEAT repeat	99..120	CDD:293787	9/22 (41%)
		HEAT repeat	133..161	CDD:293787	9/27 (33%)
		HEAT repeat	181..211	CDD:293787	4/29 (14%)
		HEAT repeat	226..252	CDD:293787	6/34 (18%)
		HEAT repeat	265..293	CDD:293787	6/57 (11%)
		HEAT_2	392..507	CDD:290374	28/126 (22%)
		HEAT repeat	395..426	CDD:293787	9/37 (24%)
		HEAT_EZ	411..465	CDD:290247	18/58 (31%)
		HEAT repeat	438..468	CDD:293787	9/29 (31%)
		HEAT repeat	484..510	CDD:293787	5/25 (20%)
		HEAT repeat	527..552	CDD:293787	7/29 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000