Protein Alignment Blm and recql5

DIOPT Version :10

• Sequence 1: NP_524319.2
• Gene: Blm / 41366
• FlyBaseID: FBgn0002906
• Length: 1487
• Species: Drosophila melanogaster
• Sequence 2: XP_073801346.1
• Gene: recql5 / 566553
• ZFINID: ZDB-GENE-071214-1
• Length: 933
• Species: Danio rerio
• Alignment Length: 809
• Identity: 254/809 - (31%)
• Similarity: 381/809 - (47%)
• Gaps: 133/809 - (16%)

  Fly   729 LSYSFGLKSFRPNQL-QVINATLLGN-DCFVLMPTGGGKSLCYQLPAILTEGVTIVISPLKSLIF 791
            |...||.:.||..|. :.:||.|.|: |.||.||||.||||||||||::..|||:|||||.:||.
Zfish     8 LKTHFGFEKFRSRQQEEAVNALLQGDRDVFVCMPTGAGKSLCYQLPALMASGVTLVISPLIALIQ 72

  Fly   792 DQINKLASLDICAKSLSGEQKMADVMAIYRDLESQPPMVKLLYVTPEKISSSARFQDTLDTLNSN 856
            ||:..|.:|::.|:|::.:..:|:...|..||||:.|.:||||:|||.::|.: ||..|.:|:|.
Zfish    73 DQVEHLKALNVPARSINSKLPLAERRQILADLESETPRLKLLYITPEMVASPS-FQPVLSSLSSR 136

  Fly   857 NYISRFVIDEAHCVSQWGHDFRPDYKKLGVLKKRFPNVPTIALTATATPRVRLDILAQLNLKNCK 921
            ..:....:|||||||||||||||||.|||.|:.|...:..|||||||..||:.||...|.|::..
Zfish   137 GLLGYLAVDEAHCVSQWGHDFRPDYLKLGDLRSRLQGIRCIALTATAPKRVKEDIERSLRLRSPL 201

  Fly   922 WFLSSFNRSNLRYRV-----LPKKGVSTLDDISRYI-RSKPQHFSGIIYCLSRKECDETSKKMCK 980
            .|.:...|.||:|.|     ||:..|..|......: .:..:...||:||.:|:.|:|.:.|:.|
Zfish   202 VFSTPVFRKNLKYDVIFRDLLPEPYVHLLAFAKEALGGNTAEKGCGIVYCRTRESCEEVAHKLTK 266

  Fly   981 DGVRAVSYHAGLTDTDRESRQKDWLTGKMRVICATVAFGMGIDKPDVRFVLHYSLPKSIEGYYQE 1045
            .|:.|..|||||...||...|.||:..|:.:|.||::||||:||.:||||:|::|.||:..||||
Zfish   267 LGIAAKPYHAGLKSGDRSENQADWMADKVPIIVATISFGMGVDKANVRFVVHWNLAKSLASYYQE 331

  Fly  1046 AGRAGRDGDVADCILYYNYSDM----LRIKKMLDSDKALQYNVK---KIHVDNLYRIVGYCENLT 1103
            :|||||||..:.|.:||:..|.    ..|:|.:...:..:.:.|   |..:.:...:|.:||. .
Zfish   332 SGRAGRDGLPSSCRIYYSPKDRDQLNFLIRKEISRKQEKRGSEKEQDKAPILDFEAMVAFCEQ-E 395

  Fly  1104 DCRRAQQLDYFGEHFTSEQCLENRETACDNCINKRAYKAVDALEHARKAARAVKDLCSGRSRFTL 1168
            .||.|....:||..      ..|...|||.|.:.:..:|    :.||.||.:        :|...
Zfish   396 GCRHATISTFFGNE------KPNCAGACDFCRDPKLVRA----QLARAAALS--------TRTNP 442

  Fly  1169 LHIA----------DVLKGSKIKKIIDFNHHKTPHHGVLKDWDKNDVHRLLRKMVIDGFLREDLI 1223
            .|.|          ::..|.  :|...|..|...:.....|.:|.      :|...|.|.:
Zfish   443 THSAEPRGPFGFDPELYAGG--RKGYGFERHDEEYGSEEDDSEKR------KKQFGDLFKK---- 495

  Fly  1224 FTNDFPQAYLYLGNNISKLMEGTPNFEFAVTKNA----------KEAKAAVGSVSDGATSSTADG 1278
                  |..|..|::..|.....|:.: .|.|:|          |..:..:..:.:..:|.:.|.
Zfish   496 ------QMSLRKGSDAPKETFVPPDAD-CVLKDASSQRIPRLTVKSREHCLSLLQECLSSHSGDA 553

  Fly  1279 QSGMREIHERCYTDLLDLCRTIASQ--RNVTMASIMNIQALKSMAE-----TLPITEKDMC---- 1332
            :.    :|.   ::.||....|..:  ::...|:|.....||.::|     ::.:||:..|
Zfish   554 EF----LHR---SEALDQAVDIEHEIFKSSKSANIYKAAVLKRVSEMKKSTSVSVTEEKPCESAE 611

  Fly  1333 -------SIPHV---TKANFDKYGAKLLEITSNYASEKLLMQAVLDEEEEQAAAKQRPSTSGWNN 1387
                   |..|:   |.|: ..|..|...:.:.:.....|.|...|..:   ::.|.|..|....
Zfish   612 EKPTCSSSAQHLDGFTSAS-QIYSLKRKRVGAGFRGSSSLFQPAGDLLK---SSDQTPGDSTCEE 672

  Fly  1388 ESVDWDMAVASQGNANTS---GASGFNSFRAGKRKKIYKSGASKRYKTSTTSPAARKTTSARGRG 1449
            ||     ....:.|.|||   ..||.:|......||:.:       |....:.|||.|.......
Zfish   673 ES-----GKTQKDNNNTSSIKAKSGSSSSLNSPSKKLSR-------KQQKLAEAARDTRLISLYF 725

  Fly  1450 GRAGAKR------------AESSASSASG 1466
            |:..|:|            .|..::||:|
Zfish   726 GKKQAQRESSPEPEETEDACEDRSASANG 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Blm	NP_524319.2	RecQ	733..1217	CDD:440280	194/508 (38%)
		HRDC	1283..1357	CDD:470625	18/94 (19%)
recql5	XP_073801346.1	None