Protein Alignment pros and prox2

DIOPT Version :9

• Sequence 1: NP_001247045.1
• Gene: pros / 41363
• FlyBaseID: FBgn0004595
• Length: 1835
• Species: Drosophila melanogaster
• Sequence 2: NP_001121764.2
• Gene: prox2 / 100003863
• ZFINID: ZDB-GENE-081003-3
• Length: 582
• Species: Danio rerio
• Alignment Length: 569
• Identity: 164/569 - (28%)
• Similarity: 233/569 - (40%)
• Gaps: 158/569 - (27%)

  Fly  1325 HAAAAAAMSAQQQQQQSGDPGANTNPNS-GPANPTNSSLSTLNIPPPHIRPSPTAAAMFQAPKTP 1388
            |..|..|......:..:|.|.|.|:..: ......|.....|   |.|..||.|.::
Zfish   110 HLQAKRARVENIIRGMAGSPNARTHGEADSDCRKENKRKQRL---PQHQEPSRTKSS-------- 163

  Fly  1389 QGMNPVAAAALYNSMTGPFCLPPDQQ----QQQQTAQQQQSAQQQQQSSQQTQQQLEQNEAL--- 1446
                                  .|::    ::|..:.|:...|.|::.|....|...:||.|
Zfish   164 ----------------------KDEECHKLKEQLQSMQRLLHQLQEKISHVYDQNYLENEELDDD 206

  Fly  1447 -----------SLVVTPKKKRHKVTDTRITPRTVSRILAQDGVVPPTGGPPSTPQQQQQ-QQQQQ 1499
                       ...|...::..|...:|....::..:..:.....|...||...:.:.. .....
Zfish   207 RSENQTFGFSSDRAVKSFQETLKCELSRTVSESIDMVFKKLSKSLPKQSPPQHAETENAINPDSH 271

  Fly  1500 QQQQQQQQQQASNGGNSNATPAQS-----PTRSSGGAAYHPQPPPPPPPMMPVSLPTSVAIPNPS 1559
            .:|...::...|.....:.|.|.|     |:.|.|  ...|.|....|.....|.|
Zfish   272 SEQSDSEEMPKSRSSFEDQTEALSLVVRKPSLSQG--VKRPFPLHQTPFQFGYSAP--------- 325

  Fly  1560 LHESKV------FSPYSPF------------FNPHA-----------AAGQATAAQLHQHHQQHH 1595
            ||:|::      |.|:|.|            .:|.:           .:|.|.|.  ||...||.
Zfish   326 LHDSQILEHLLKFGPHSAFSALPCLPATLERASPESLDHPWESVRSKVSGAAAAG--HQLQLQHQ 388

  Fly  1596 PHHQSMQLSSSPPGSLGALMDSRDSPPLPHPPSMLHPALLAAAHHGGSPDYKTCLRAVMDAQDRQ 1660
                    .::|.|.|..     ||..|||                          ..|:..|.|
Zfish   389 --------RAAPAGLLAV-----DSLCLPH--------------------------VKMEVADLQ 414

  Fly  1661 SECNSADMQFDGMAPTSS--------TLTPMHLRKAKLMFFWVRYPSSAVLKMYFPDIKFNKNNT 1717
            |           ||..||        .|||.||:|||||||:.|||||.:||.:|||:|||:..|
Zfish   415 S-----------MADRSSYMALNIQEGLTPNHLKKAKLMFFYTRYPSSNLLKNFFPDVKFNRCIT 468

  Fly  1718 AQLVKWFSNFREFYYIQMEKYARQAVTEGIKTPDDLLIAGDSELYRVLNLHYNRNNHIEVPQNFR 1782
            :||:||||||||||||||||:||||:.:|:....|:.::.:|||:|.||:|||:.|..:||..|.
Zfish   469 SQLIKWFSNFREFYYIQMEKFARQAIIDGVTDVKDISVSRESELFRALNMHYNKANDFQVPDRFL 533

  Fly  1783 FVVESTLREFFRAIQGGKDTEQSWKKSIYKIISRMDDPVPEYFKSPNFL 1831
            .|.|.||:||:.||...||::.||||:|||:|.::|..|||.||||::|
Zfish   534 EVAEVTLQEFYSAISLSKDSDPSWKKAIYKVICKLDSDVPEEFKSPSYL 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pros	NP_001247045.1	HPD	1679..1830	CDD:282848	89/150 (59%)
prox2	NP_001121764.2	HPD	430..581	CDD:282848	89/150 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592752
Domainoid	1	1.000	205	1.000	Domainoid score	I2882
eggNOG	1	0.900	-	-		E1_KOG3779
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	284	1.000	Inparanoid score	I2847
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003482
OrthoInspector	1	1.000	-	-		otm26310
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12198
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.940