DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment KP78a and LOC690235

DIOPT Version :9

Sequence 1:	NP_650066.1	Gene:	KP78a / 41362	FlyBaseID:	FBgn0026064	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	XP_038938164.1	Gene:	LOC690235 / 690235	RGDID:	1582875	Length:	502	Species:	Rattus norvegicus

Alignment Length:	505	Identity:	155/505 - (30%)
Similarity:	253/505 - (50%)	Gaps:	64/505 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 SKNTDSKFQSYVNGNGNGVYKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLY 143
            |:...|:..||.. :.:..|.|:.|:|.|.:|.||||:|..||..||:|::.|.:   .....:.
  Rat     9 SERLPSEGSSYTE-SFHSQYMILNTIGHGGYATVKLALHRLTGTPVAVKILIKKE---HWCHPVT 69

  Fly   144 REVKIMKLLNHPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAI 208
            .||.||..::||||:.||||||:::.:||:||.|...:|:..:.:.|:::|.:||.|||||:||.
  Rat    70 SEVDIMMSIHHPNIISLFQVIETKKKIYLIMELAEGKQLYHRIREAGQLQEDEARGIFRQLLSAT 134

  Fly   209 QYCHSKFVVHRDLKAENLLLDQHMNIKIADFGFGNTFDPNAQLETFCGSPPYAAPELFMGRKYAG 273
            .|||::.:||||||.:|:::|....|||.|||......|..:|...||:..:||||:.:|:.|.|
  Rat   135 GYCHARGIVHRDLKPDNIMIDTRGRIKIIDFGLATHVRPGQKLRYHCGTYAFAAPEMLLGKLYEG 199

  Fly   274 PEVDAWSLGVVLYTLVSGSLPFDGGTLKELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAKRT 338
            |:||.|:||||||.:..|.||||...:.:||.:|:.|||.||..:|.:.::::...|.:||..|.
  Rat   200 PKVDVWTLGVVLYCMTVGRLPFDDSNIPQLRSQVVSGKYAVPPGMSGELKDMLSLLLKVNPQHRP 264

  Fly   339 SLSAVMSDKWINLGHD----ESDRLRPFREKPMELQDAARFDLLMSMGHKRRDVEQSVKGQLFDD 399
            ::..:::..|:..|.:    .|:...|.|..|..|:      .:..:|.|.:||:.|:....::.
  Rat   265 TIPDLLTHPWLKTGSEGFPQPSEEWIPLRPDPAVLR------AMEQIGFKAQDVKDSLYQNKYNQ 323

  Fly   400 IYCTYMLLGVAKPRSSNRSTKPEAIPTVDLTTPAVSSPLPNITTPTVTIAHVTLALDKNPPIHSS 464
            ....|.||.....:..:.||:|..:      .|.: :|.|::               .||.....
  Rat   324 TVACYHLLERQALQGCDNSTRPGPM------NPWM-APFPSL---------------DNPATFPQ 366

  Fly   465 SASGRPIAPR-LANAPNTPTST----P----------PTGPPAKPTRRTPA--------RTPARK 506
            ....|...|| |.::.|:..||    |          |.|...:|...|||        |:....
  Rat   367 ELRRRGSEPRWLGSSSNSQGSTYDQKPSYGLVKRASWPGGRLCRPLLTTPAVDLTNRISRSVPCF 431

  Fly   507 ATNHTSGQGRPEPSSLPHTPQSKRASANMDVKPTLLSAQRQLAQTQKLAN 556
            ::.|:.|:     .::..|.....|||.::..|:....:|.....:.:.|
  Rat   432 SSVHSRGE-----KNIKSTEDKSSASAEVNPVPSRAWPKRFRGWAKNIGN 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KP78a	NP_650066.1	PKc_like	98..349	CDD:304357	104/250 (42%)
KP78a	NP_650066.1	S_TKc	98..349	CDD:214567	104/250 (42%)
LOC690235	XP_038938164.1	STKc_AMPK-like	26..274	CDD:270905	104/250 (42%)
LOC690235	XP_038938164.1	UBA_MARK_Par1	294..333	CDD:270522	10/44 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910