Protein Alignment KP78a and snrka

DIOPT Version :10

• Sequence 1: NP_650066.1
• Gene: KP78a / 41362
• FlyBaseID: FBgn0026064
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_001180256.1
• Gene: snrka / 436661
• ZFINID: ZDB-GENE-040718-84
• Length: 804
• Species: Danio rerio
• Alignment Length: 643
• Identity: 199/643 - (30%)
• Similarity: 296/643 - (46%)
• Gaps: 117/643 - (18%)

  Fly    91 NGNGNGVYKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYREVKIMKLLNHP 155
            :|...|:|.:.||||:|:||.||||.||.||.:||:||||||:|:|.|...|::||:.|||:.||
Zfish     9 DGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTVATGHLFQEVRCMKLVQHP 73

  Fly   156 NIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGR-MRERDARVIFRQLVSAIQYCHSKFVVHR 219
            |||||::||:::..|||::|....|::||:::|:.. :.|..|:..|.|:|.||.|||...||||
Zfish    74 NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEELAKKYFAQIVHAISYCHRLHVVHR 138

  Fly   220 DLKAENLLLDQHMN-IKIADFGFGNTFDPNAQLETFCGSPPYAAPELFMGRKYAGPEVDAWSLGV 283
            |||.||::..:... :|:.||||.|.|.|..:|.|.|||..|:|||:.:|.:|..|.||.|||||
Zfish   139 DLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGV 203

  Fly   284 VLYTLVSGSLPFDGGTLKELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAKRTSLSAVMSDKW 348
            :|:.||.|..||......|....::..||.||.::|..|::|:.:.|..:|.:|.||..:.|..|
Zfish   204 ILFMLVCGQPPFQEANDSETLTMIMDCKYTVPAHVSNACKDLINRMLQRDPKRRASLEEIESHAW 268

  Fly   349 I-------------------NLGHDESDRLRPFREKPMELQDAARFDLLMSMGHKRRDVEQSVKG 394
            :                   ||..:|.:.:    .:.|.|.|.|          .|..:.::::.
Zfish   269 LQGVDPSPATKYNTPLVSHKNLSEEEHNSI----IQRMVLGDIA----------DREAIVEALET 319

  Fly   395 QLFDDIYCTYMLLG----------VAKPRSSNRSTKP----EAIPT-----VDLTTPAVSSPL-- 438
            ..::.|..||.||.          ..:||||:.|...    ::.||     .|:.....||.:
Zfish   320 NKYNHITATYFLLAERILREKQEKEVQPRSSSPSNIKAQFRQSWPTKNDLHQDIEDSLASSSICH 384

  Fly   439 ------PNITTPTVTIAHVT---LALDKNPPIHSSSASGRPIAPRLANAPNTPTSTPPTGPPAKP 494
                  |..:...:...|..   |.:.:...|..:|:|          :| .|.|.||.  |.||
Zfish   385 AGGPQSPARSAENLLNGHRNKGLLEVSRREEICEASSS----------SP-APASLPPN--PLKP 436

  Fly   495 TRRTP-ARTPARKAT------NHTSGQGRPEPSSLPHTPQSKRASANMDVKPTLLSAQRQLAQTQ 552
            ....| |...|::.|      .....:...|||.||.....:|       ||        |:.|.
Zfish   437 GVMAPLASASAKQRTCLFRVEEDEEEEEEQEPSPLPTQVVLRR-------KP--------LSITN 486

  Fly   553 KLANTPPRFQYPVAQTPNQAQGSSRRPTTLYEKAEPAVTPL-LVPKSPAMGARLLERIPGGG--- 613
            :|.:   |...||.....:.:|.|.....:.|...|.::.| :...||....:...|....|
Zfish   487 RLTS---RKSAPVLNQIFEEEGESDDDFDMDESLPPKLSRLKMNMTSPGTAQKRYPRRKSQGRGS 548

  Fly   614 --AVEKTS--DKPFTRQNVARAT-FHFGQAR----SGKRGGGSGNGAGGEEDSYQTPP 662
              :..:||  |....|:.:.:.| |.:...|    .|..|...||| ||.......||
Zfish   549 SCSSSETSDDDSESHRRRLDKDTGFTYSWNRRDSSEGPPGNSGGNG-GGSSGGQSKPP 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78a	NP_650066.1	Protein Kinases, catalytic domain	98..349	CDD:473864	116/252 (46%)
		UBA_MARK_Par1	370..408	CDD:270522	7/37 (19%)
snrka	NP_001180256.1	STKc_SNRK	12..269	CDD:270976	117/256 (46%)
		UBA_SNRK	288..335	CDD:270524	13/60 (22%)