DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment KP78a and Pask

DIOPT Version :9

Sequence 1:	NP_650066.1	Gene:	KP78a / 41362	FlyBaseID:	FBgn0026064	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_611864.1	Gene:	Pask / 37824	FlyBaseID:	FBgn0034950	Length:	985	Species:	Drosophila melanogaster

Alignment Length:	310	Identity:	90/310 - (29%)
Similarity:	155/310 - (50%)	Gaps:	20/310 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 TSNATALPATPTVAAGQDLGDGAC---SSKNTDSKFQSYVN----GNGNGVYKIIKTLGKGNFAK 111
            ||...::.:|...:.||.:...|.   |..|:.|....|.:    |:.:..|..|:.:|:|.:..
  Fly   525 TSTFNSMASTVEQSLGQVIKTTAAQNSSRPNSLSLVSKYEDELYLGDYSKYYTSIRQIGRGAYGY 589

  Fly   112 VKLAIHVPTGREVAIKVIDK----TQLNTSAR--QKLYREVKIMKLLNHPNIVRLFQVIESERTL 170
            |.:|........|..|.|.|    :|....:|  :::..|:.:::.|||.|||.:..|.|::...
  Fly   590 VNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVPIEIHLLQTLNHKNIVSVLDVFENDLFY 654

  Fly   171 YLVME-YASRGELFDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVHRDLKAENLLLDQHMNI 234
            .|||| :.|..:|:..:.:...|.|:....||||:..|:.|.|.:.::|||:|.||:::||:..|
  Fly   655 QLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQVADAVNYLHEQKILHRDIKDENIIIDQNFTI 719

  Fly   235 KIADFGFGNTFDPNAQLETFCGSPPYAAPELFMGRKYAGPEVDAWSLGVVLYTLVSGSLPFDGGT 299
            |:.|||.....:......||.|:..|.:||:..|.:|.|||::.|:|||.||.|:....||..
  Fly   720 KLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGNRYVGPELEIWALGVTLYVLMFFENPFID-- 782

  Fly   300 LKELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAKRTSLSAVMSDKWI 349
                .|..|:.:.::|..:|.....|:...|..:|..|.::..:::|.|:
  Fly   783 ----VEETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRCTMHQLITDPWL 828

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KP78a	NP_650066.1	PKc_like	98..349	CDD:304357	78/257 (30%)
KP78a	NP_650066.1	S_TKc	98..349	CDD:214567	78/257 (30%)
Pask	NP_611864.1	PAS_9	74..169	CDD:290162
		PAS	74..169	CDD:238075
		PAS_9	286..>335	CDD:290162
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	78/258 (30%)
		S_TKc	576..828	CDD:214567	78/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24346
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010