Protein Alignment KP78a and Sik3

DIOPT Version :9

• Sequence 1: NP_650066.1
• Gene: KP78a / 41362
• FlyBaseID: FBgn0026064
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_001188969.1
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Alignment Length: 749
• Identity: 248/749 - (33%)
• Similarity: 347/749 - (46%)
• Gaps: 196/749 - (26%)

  Fly    39 TIVTTGATAQPATPTTSNATALPATPTVAAGQDLGDGACSSKNTDSKFQSYVNGNGNGVYKIIKT 103
            |..|.|..|.|.|.:|.....:|:|..::..:.|                     ..|.|::.||
  Fly     3 TTPTAGPAAAPPTSSTPQNYKVPSTSKISVDKLL---------------------RVGYYELEKT 46

  Fly   104 LGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYREVKIMKLLNHPNIVRLFQVIESER 168
            :||||||.||||.::.|..:||||:||||.||.....|.:||:.|:|.|.||:|.||::|:||:.
  Fly    47 IGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEYLNKTFREIAILKSLRHPHITRLYEVMESQS 111

  Fly   169 TLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVHRDLKAENLLLDQHMN 233
            .:|||.|||..||:|||||.||||:|.:|..:|.|||||:.|||.:.||||||||||:|||:.||
  Fly   112 MIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMN 176

  Fly   234 IKIADFGFGNTFDPNAQLETFCGSPPYAAPELFMGRKYAGPEVDAWSLGVVLYTLVSGSLPFDGG 298
            ||:|||||.|.::..|.|:|:||||||||||:|.|.:|.||:.|.||||||||.||.|:|||||.
  Fly   177 IKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVVLYALVCGALPFDGK 241

  Fly   299 TLKELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAKRTSLSAVMSDKWINLGHDESDRLRPF- 362
            |:.||:.||:.||:|:|:::|.:||.|:|..||:.|.:|.::..::..:|::....|......|
  Fly   242 TILELKSRVVLGKFRIPFFMSQECEQLIRNMLVVEPDRRYTIKQIIKHRWLSEWQSEMQEQERFG 306

  Fly   363 ---------------------REKPMELQDAARFDLLMSMGHKRRDVEQSVKGQLFDDIYCTYML 406
                                 .:.|.:|.......:|...|.....:.|||..|.||:||..|.|
  Fly   307 DMSPGSGTVSKSASTSSLGSASDSPPQLDSVVMTHMLQLPGLTADMIAQSVHEQRFDNIYAIYNL 371

  Fly   407 L--GVAKPRSSN------------RSTKPEAIPT--VDLTTPAVS------SPLPNITTPTVTI- 448
            |  .:.:.|..|            ||.| .:|.|  ||.:.|...      |||.|....:..:
  Fly   372 LHDKLQQRRRENQRLQHHASLAYSRSRK-TSITTGVVDRSEPVKQESLDRLSPLSNANASSSALG 435

  Fly   449 ---AHVTLALDK-------------NPPI---HSSSASGRPIAPRLANAPNTPTSTPPTGPPAKP 494
               :.|.:.|:|             :||:   |.|:.:|..:     |..|
  Fly   436 FGWSDVAVDLEKYGDFELECLARSNDPPVNAQHLSAHAGGGV-----NGAN-------------- 481

  Fly   495 TRRTPARTPARKATNHTSGQGRPEPSSLPHTPQSKRASANMDVKPTLLSAQRQ------------ 547
            |||            ||.|     |..:.|    ::|.||.:|.|.......|
  Fly   482 TRR------------HTVG-----PGDVAH----EQALANPNVPPIDFKCPPQCSDPTQPVPYYP 525

  Fly   548 ----LAQTQKLANTPPRFQYPVAQTPNQAQGSS---RRPTT------LYEKAEPAVTPLLVPKSP 599
                :.|.|.|.|...:.|:.:  .|....|:|   ||.:.      :|..|...|.      .|
  Fly   526 VNLPMLQNQPLHNLTIKDQHLL--KPPVVMGASSFGRRASDGGANLHIYYPATGTVV------GP 582

  Fly   600 AMGARL----LERIPGGG----AVEKTSDKPFTRQNVAR-------ATFHFG---QARSGKRGG- 645
            |.|.::    ....|..|    ||::.|  |...|:||:       ||....   |:...||||
  Fly   583 AQGQQMDTAGYYINPNCGTDPLAVQELS--PLNEQSVAQMQCCQENATGECNEELQSYMQKRGGT 645

  Fly   646 -------------GSGNGAGGEEDSYQTPPLSAD 666
                         ..|:|||.:.   |.|..|::
  Fly   646 QRHTVGCTEDLSVAHGSGAGSQS---QAPTTSSN 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78a	NP_650066.1	PKc_like	98..349	CDD:304357	142/250 (57%)
		S_TKc	98..349	CDD:214567	142/250 (57%)
Sik3	NP_001188969.1	PKc_like	40..292	CDD:304357	142/251 (57%)
		S_TKc	41..292	CDD:214567	142/250 (57%)
		UBA_SIK	335..380	CDD:270523	13/44 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810