Protein Alignment KP78a and Smok2b

DIOPT Version :9

• Sequence 1: NP_650066.1
• Gene: KP78a / 41362
• FlyBaseID: FBgn0026064
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_001161385.1
• Gene: Smok2b / 236574
• MGIID: 3037705
• Length: 484
• Species: Mus musculus
• Alignment Length: 463
• Identity: 136/463 - (29%)
• Similarity: 242/463 - (52%)
• Gaps: 57/463 - (12%)

  Fly    93 NGNGVYKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYREVKIMKLLNHPNI 157
            |.:..|.:::|:|.|..:||.||.|..||..||:|:|.|::...:   .:..||:::.:.:||||
Mouse     3 NFHAQYVMLETIGHGGCSKVMLARHRLTGSHVAVKMIRKSECWCN---PVMSEVELLMMADHPNI 64

  Fly   158 VRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVHRDLK 222
            :.|.||||:::.:||:||......|:.|:...|.::|.:||.:|:||:||:.|||::.:||||||
Mouse    65 ISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGYLQEDEARALFKQLLSAMNYCHNQGIVHRDLK 129

  Fly   223 AENLLLDQHMNIKIADFGFGNTFDPNAQLETFCGSPPYAAPELFMGRKYAGPEVDAWSLGVVLYT 287
            .:|:::::...:||.|||.|....|..:|..|||:.|::|||:.:.|.|.||::|.|:||||||.
Mouse   130 PDNIMVEKDGKVKIIDFGLGTQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYF 194

  Fly   288 LVSGSLPFDGGTLKELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAKRTSLSAVMSDKWINLG 352
            :|:|.:|||..::::|..::|.|||.||..:|::..:|:...:..||..|.:::.||...|:..|
Mouse   195 MVTGKVPFDAASIQKLVRQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWVTEG 259

  Fly   353 H----DESDRLRPFREKPMELQDAARFDLLMSMGH---KRRDVEQSVKGQLFDDIYCTYMLLGVA 410
            .    |..:...|.:..|.         ::.:||:   :.:|:|.|::.:.|::...:|.||...
Mouse   260 SGVFPDPCEEQMPLKPNPA---------IVKAMGYIGFQAQDIEDSLRQRKFNETMASYCLLKKQ 315

  Fly   411 KPRSSNRSTKPEAIPTVDLTTPAVSSPLPNI--------------TTPT---------VTIAHVT 452
            ..:..:|..:.:.:      .|:| :|.|::              |.||         :::...:
Mouse   316 ILKECDRPIRAQPM------NPSV-TPFPSLVDTSTFHLGLRRRETEPTSLRLSANRQMSVCGRS 373

  Fly   453 LALDKNPPIHSSSASGRPI-APRLANAPNTPTSTPP-------TGPPAKPTRRTPARTPARKATN 509
            .:..::......|.||||: .....:..:|.|.:.|       |..|......|...|.|.....
Mouse   374 TSKKRDRRFSWPSVSGRPLHTTHTMDHTHTRTRSVPCIYSMFCTIQPNSSDDSTEGHTSASAEDK 438

  Fly   510 HTSGQGRP 517
            ....:|.|
Mouse   439 PVRSRGWP 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78a	NP_650066.1	PKc_like	98..349	CDD:304357	98/250 (39%)
		S_TKc	98..349	CDD:214567	98/250 (39%)
Smok2b	NP_001161385.1	STKc_AMPK-like	7..255	CDD:270905	98/250 (39%)
		S_TKc	8..256	CDD:214567	98/250 (39%)
		UBA_MARK_Par1	275..314	CDD:270522	10/47 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	356..400		7/43 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..450		5/25 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810