Protein Alignment KP78a and kin-29

DIOPT Version :9

• Sequence 1: NP_650066.1
• Gene: KP78a / 41362
• FlyBaseID: FBgn0026064
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_508493.1
• Gene: kin-29 / 180574
• WormBaseID: WBGene00002210
• Length: 822
• Species: Caenorhabditis elegans
• Alignment Length: 739
• Identity: 213/739 - (28%)
• Similarity: 316/739 - (42%)
• Gaps: 205/739 - (27%)

  Fly    96 GVYKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYREVKIMKLLNHPNIVRL 160
            |:|.:.:.:||||||.|::|.|.....:||||.||.:.|:.....||.|||||:|:::||:||:.
 Worm    14 GLYDVGRAIGKGNFATVRIARHKIAKTKVAIKSIDVSALDRENLIKLEREVKIVKVIDHPHIVKS 78

  Fly   161 FQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVHRDLKAEN 225
            ::::..:..||:|.||.|.|||::.|::.||:.|..||..|.:..||:.|.||:.:|||||||||
 Worm    79 YEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENVARKWFSETASAVAYLHSQGIVHRDLKAEN 143

  Fly   226 LLLDQHMNIKIADFGFGNTFDPNAQLETFCGSPPYAAPELFMGRKYAGPEVDAWSLGVVLYTLVS 290
            :||.::.||||.||||.|....:..|.|:|||||||||||.:|..|.|.:.|.||:||:||.||:
 Worm   144 ILLGKNSNIKIIDFGFSNFQTGDQLLNTWCGSPPYAAPELLLGNSYDGMKADIWSMGVLLYILVA 208

  Fly   291 GSLPFDGGTLKELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAKRTSLSAVMSDKWINLGHD- 354
            |..||...::.:|:..||.|..::||::|::|.:.:||.|||||.||.::..|:..:|:::..|
 Worm   209 GGFPFPSDSVNKLKRSVLSGLVKIPYWVSVECADFIRKMLVLNPGKRYTIQNVLQHRWMHIRDDV 273

  Fly   355 ----ESDRLRPFREKPMEL-QDAARFD---LLMSMGHKRRDVEQ---SVKGQLFDD-IYCTYMLL 407
                .:..|.......:|: |.:.:.:   ::....|.:...||   :|.|:.|:. |:.||.||
 Worm   274 QKNQAAQLLEAIPSSSIEIRQQSTKLNPTIMMFMQQHGKWSEEQIIDAVLGRDFESPIFATYELL 338

  Fly   408 ------------GVAKPRSSNRSTKPEAIPTVDLTTPAVSSPLPNITTPTVT---IAHVTLA--- 454
                        |...||..:|.:.......||      ..||    |||::   :|.:.|:
 Worm   339 ADKVKKGTLEGTGEEFPRRGSRGSILSGKANVD------EQPL----TPTISAHQLAQLNLSSPD 393

  Fly   455 -----------LDKNP-----PIHSSSASGRP-----IAPRLAN------------APNTP---- 482
                       .|.:|     |::.....|.|     |..|..|            :||..
 Worm   394 CDSDDSSNSDLCDDSPMSSMGPMNHERQFGTPHGLDIIGNRFENRRHTLCASEQLLSPNMMGQFP 458

  Fly   483 ---------TSTPPTGPPAKPTRRTPARTPARKATNHTSGQGR--PEPS---------------S 521
                     :..||.|.|..|                 .||..  |.||               .
 Worm   459 PPNLLLNNFSMNPPLGFPPMP-----------------EGQAAEFPLPSLHPAFATIPIADLSKM 506

  Fly   522 LPHTPQSKRASANMDVKPTLLSAQRQLAQTQKLANTP-PRFQYPVAQTP---------------- 569
            ||.....:||||...:.||      ....||.|||.| |...:|..:..
 Worm   507 LPVPKSERRASAGETLLPT------NFDLTQHLANLPAPPISFPTVEEEGKSYLSKYGGKRNTVH 565

  Fly   570 ---NQAQGSSRRP-----TTLYEKAEPA------VTPLLVPKSPAMGARLLERIPGGGAVEKTSD 620
               ||..|..:.|     .|.|.||.||      .:|.|..:......:|.::     |::..:|
 Worm   566 CLGNQLGGGIQNPIPRYQRTPYTKAPPAERRSSWASPSLSAQQQNHLEKLFKQ-----ALQTNND 625

  Fly   621 KPFTRQNVARATFHFGQARSGKRGGGSGNGAGGEEDSYQTPPLSADD------------------ 667
              .||.:........|.|:|.....||         |...|.:|..|
 Worm   626 --MTRLHKEFKGLSHGCAQSQITNEGS---------SLACPQISITDEYNRQHNIAPSASSFDPV 679

  Fly   668 -------------TKPASRVGFFS 678
                         .:||:.:||.|
 Worm   680 SIFQKNAQEVVFGQRPATAIGFSS 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78a	NP_650066.1	PKc_like	98..349	CDD:304357	116/250 (46%)
		S_TKc	98..349	CDD:214567	116/250 (46%)
kin-29	NP_508493.1	PKc_like	16..267	CDD:304357	116/250 (46%)
		S_TKc	16..267	CDD:214567	116/250 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.870