Protein Alignment KP78a and txt-2

DIOPT Version :10

• Sequence 1: NP_650066.1
• Gene: KP78a / 41362
• FlyBaseID: FBgn0026064
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_872128.2
• Gene: txt-2 / 178551
• WormBaseID: WBGene00019817
• Length: 328
• Species: Caenorhabditis elegans
• Alignment Length: 292
• Identity: 94/292 - (32%)
• Similarity: 152/292 - (52%)
• Gaps: 20/292 - (6%)

  Fly    78 SSKNTDSKFQSYVNGNGNGVYKIIKTLGKGNFAKVKLAIHVPTGREV-AIKVIDKTQLNTSARQK 141
            |:.:|..:|.| ........|:.|:.||:|:||:|.|...|.|..:: |:|.|.....:....:.
 Worm     3 SNMSTCKQFLS-TKKKSKDSYEFIENLGEGSFAEVVLVAKVGTPNKMFAMKEISIVGKDECFMES 66

  Fly   142 LYREVKIMKLLN---HPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQ 203
            :.||..|.|.|:   |.|::.||::..:.....|::.||..|:||:.:.::|.:...:|...|:|
 Worm    67 IKRECSIQKRLSKSRHLNMIHLFEIRTNPENYQLILSYADGGDLFEKINQHGGLGSDEAHRYFKQ 131

  Fly   204 LVSAIQYCHSKFVVHRDLKAENLLLDQHMNIKIADFGFGNTFDPNA---QLETFCGSPPYAAPEL 265
            |:..:::.|.:.|.|||:|.|||||.:...:|||||||......|.   .|..:||||||.|||:
 Worm   132 LIDGLRFIHEEGVTHRDIKPENLLLTKSGILKIADFGFATMHRFNGAEQMLNAYCGSPPYIAPEV 196

  Fly   266 FMGRKYAGPEVDAWSLGVVLYTLVSGSLPFDGGTLKEL--------RERVLRGKYRVPYYISMDC 322
            ..|..|.||.||.||.||||..:::|::|::.....::        |....:|.:.   .:|...
 Worm   197 LTGIDYRGPAVDIWSAGVVLIAMIAGAVPWEQADHFDIFQSRYCSFRRNGRKGAWS---RMSQQV 258

  Fly   323 ENLMRKFLVLNPAKRTSLSAVMSDKWINLGHD 354
            .:|:||.| |....|.::|.:..|.|...|.:
 Worm   259 ISLLRKIL-LQAELRATISMIEEDPWFIYGEE 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78a	NP_650066.1	Protein Kinases, catalytic domain	98..349	CDD:473864	88/265 (33%)
		UBA_MARK_Par1	370..408	CDD:270522
txt-2	NP_872128.2	Protein Kinases, catalytic domain	22..284	CDD:473864	88/265 (33%)