Protein Alignment KP78b and Gm7168

DIOPT Version :9

• Sequence 1: NP_001163587.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_006524826.1
• Gene: Gm7168 / 635895
• MGIID: 3643198
• Length: 549
• Species: Mus musculus
• Alignment Length: 563
• Identity: 163/563 - (28%)
• Similarity: 256/563 - (45%)
• Gaps: 116/563 - (20%)

  Fly    14 NDPGPNTSISTTATPPSAAAQNVGGCFGSSGG-RSSPKFQSYV---------------NGNGYGV 62
            |:|....|.|...:..|.::.::...:..||| .||.|..:::               :|..|..
Mouse     4 NEPTGTQSFSERTSSGSRSSCSIQDTWNYSGGTTSSDKMPAHIEEELPPPSPQPSNPEDGELYSQ 68

  Fly    63 YKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLYREVNIMKKLNHPNIVRLLQ 127
            ||:::|||.|.:|||.||.|..||..||:|::.|   |....|...:|.|||||:.|||||.|||
Mouse    69 YKVVRTLGHGTYAKVLLAKHWLTGTPVAVKVLLK---NKPCFQPAMKEANIMKKIKHPNIVSLLQ 130

  Fly   128 VIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHSKSIVHRDLKAENLL 192
            |.|::...||:||.|.|.||:.|:..:|.:.|.:||.:|.|::||:.|||...|||||||.:|::
Mouse   131 VFETKTRGYLIMELVEGQELYEYIKSSGHIEEDEARQIFLQILSAVSYCHGLGIVHRDLKPDNIM 195

  Fly   193 LDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSGPEVDSWSLGVVLYTLVSGS 257
            :|.:..:||.|||.||..:|...|:..||:..:.|||||..|.|.|.:.|.|:|||:||.:|.|.
Mouse   196 IDDKGSIKIIDFGLSTQVKPGDLLDEHCGAYAFGAPELFLWKSYDGTKSDLWALGVILYYMVVGK 260

  Fly   258 LPFDGTNLKELRDRVLRGKYRVPYYVSIECESLIRKFLVLNPTQRTSLSAVMADRWINMGYEQGN 322
            :|||...:.||:.::|.|.|..|..||.|.:.|:...:.:||..|.:::.||...|:     :|:
Mouse   261 VPFDSYIIPELQRQILAGVYPAPCGVSNELKDLLSLLMTVNPKYRPTVTEVMKHPWL-----RGH 320

  Fly   323 --GLRPFQEKPMDLH-DVNRLSLLSNMGHKPRDVEQSLKNQKFDDIYCTYMLLD----------- 373
              ||....|:|:.:. |.:.:..:..:|.:.:|:.:||..:||:::...|.||:
Mouse   321 CKGLTNIHEEPVPVRPDPDIVDAMQYIGFQAKDIRESLTKEKFNEMSAAYYLLEEQALQREVRST 385

  Fly   374 -------------------------------------------------VAKPRSTACSEKSGSS 389
                                                             |.|.|..|....||..
Mouse   386 QAPTVSQVKAPFPSMDAGEASCLKIKRSGSASILGRSVWPPSIDQEPAYVQKVRQRAGRRSSGHG 450

  Fly   390 FRETPTAMPGSS--------RIPVPIAAPNVT-----------ISQVTFALDKSTPNRPAATSIR 435
            ....|..|..:.        .:|..::..:::           :|.:..|.||...:|.....|.
Mouse   451 LLFEPNQMTPTQDQHHIRAMSVPCMLSTSSISEESVSEKREENLSHIALAEDKPIRSRGWCRGIM 515

  Fly   436 PMAPRLANALTPLPLTPPPKKYICCSASKAANPRRSEPSSIPQ 478
            ....|:.||:          :.:||.......|:..:....||
Mouse   516 RWTRRVGNAI----------RTLCCCIPSRKTPQLGQSRVSPQ 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78b	NP_001163587.1	PKc_like	63..314	CDD:304357	111/250 (44%)
		S_TKc	63..314	CDD:214567	111/250 (44%)
Gm7168	XP_006524826.1	STKc_AMPK-like	68..316	CDD:270905	111/250 (44%)
		UBA_MARK_Par1	336..375	CDD:270522	10/38 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810