Protein Alignment KP78b and Smok3c

DIOPT Version :9

• Sequence 1: NP_001163587.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001297632.1
• Gene: Smok3c / 622486
• MGIID: 3647925
• Length: 504
• Species: Mus musculus
• Alignment Length: 579
• Identity: 172/579 - (29%)
• Similarity: 265/579 - (45%)
• Gaps: 116/579 - (20%)

  Fly    46 RSSPKFQSYVNGNGY-GVYKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLYR 109
            |..|.|.   |.:|: ..|.:::|:|.|..|.||||.|..||..||:|.|.|.....|.   :..
Mouse    13 RCKPPFS---NMDGFHAQYVMLETIGHGGCATVKLAQHRLTGTHVAVKTIQKRGYWCIL---IMS 71

  Fly   110 EVNIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIE 174
            ||:::...:|||::.||||||:::.:||:||...|..|:.::.|.|.::|.:||.||:||:||:.
Mouse    72 EVDLLMMADHPNVISLLQVIETKKKVYLIMELCEGKSLYQHIRKAGYLQEHEARALFKQLLSAMN 136

  Fly   175 YCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSGP 239
            |||::.|||||||.:|:::::..|:||.|||.||..:|...|..|||:.|::|||:.....|.||
Mouse   137 YCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLSTKVKPGQKLNLFCGTYPFSAPEVLLSTPYDGP 201

  Fly   240 EVDSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYYVSIECESLIRKFLVLNPTQRTS 304
            ::|.|:||||||.:|:|.:|||..::|.|..|:|.|||.:|..:|.|...|:...:..||..|.:
Mouse   202 KIDVWTLGVVLYFMVTGKIPFDACSIKRLVKRILAGKYSIPSRLSAELRDLLSLLMTANPKLRPT 266

  Fly   305 LSAVMADRWINMGYEQGNGL--RPFQEKPMDLHDVNRLSLLSNMGHKPRDVEQSLKNQKFDDIYC 367
            ::.||...|:.    :|:|:  .|.:|:.....|...:..:.::|.:.:|:|.||:.:||:....
Mouse   267 VAEVMVHPWVT----EGSGVFPDPCEEQTPLKPDPAIVKAMGHIGFQAQDIEDSLRQRKFNQTMA 327

  Fly   368 TYMLLDVAKPRSTACSEKSGSSFRETPTAMPGSSRIPVPIAAPNVTISQVTFALDKSTPNRPAAT 432
            :|.||.                                         .|:....|:.|..||...
Mouse   328 SYCLLK-----------------------------------------KQILKECDRPTRARPVNP 351

  Fly   433 SIRPMAPRLANALTPLPLTPPPKKYICCSASKAANPRRSEPSSIPQSAMPKKGVGSPVDVKTTLL 497
            |:.|....:..|.|.|.|.                 ||....:.|.|
Mouse   352 SVTPFPSLVDTATTCLGLR-----------------RRENEPTCPWS------------------ 381

  Fly   498 SAQRKLAVNQKLTSASHQIRSPITQSPSQASECTRTPPTHFEMLDSTSTPLKVLKLVAS---NSQ 559
            ||.|:::|..|.||.....|   ...||.......|.||    :|.|.|..:.:..:.|   ..|
Mouse   382 SANRQVSVCGKSTSKKRDRR---VSWPSVLGRPRHTAPT----MDHTRTRTRSVPCICSMFCTVQ 439

  Fly   560 TPPSTENTNRPTRVGFFSKLS------------ARFVRRSLHK-----GEKDISEQGRN 601
            ...|.|:|...||.....|..            .|.:..::.|     ..|:.|..|:|
Mouse   440 PNSSEESTQGHTRASAADKPVRSRGWPRGIKGWTRMIGNAMRKLCCCIPSKETSHLGQN 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78b	NP_001163587.1	PKc_like	63..314	CDD:304357	106/250 (42%)
		S_TKc	63..314	CDD:214567	106/250 (42%)
Smok3c	NP_001297632.1	STKc_AMPK-like	27..275	CDD:270905	106/250 (42%)
		UBA_MARK_Par1	295..334	CDD:270522	11/79 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810