Protein Alignment KP78b and mark2a

DIOPT Version :9

• Sequence 1: NP_001163587.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_009293774.1
• Gene: mark2a / 562231
• ZFINID: ZDB-GENE-030131-4145
• Length: 782
• Species: Danio rerio
• Alignment Length: 633
• Identity: 269/633 - (42%)
• Similarity: 351/633 - (55%)
• Gaps: 127/633 - (20%)

  Fly    44 GGRSSPKFQSYVNGNGYGVYKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLY 108
            ||||:....:.......|.|:::||:|||||||||||.|:.||:|||:|:||||.||:.:.|||:
Zfish    25 GGRSTMPHSTADEQPHIGCYRLLKTIGKGNFAKVKLAKHILTGKEVAVKIIDKTQLNSSSLQKLF 89

  Fly   109 REVNIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAI 173
            |||.|||.|||||||:|.:|||:|:||||||||.||||:|:|||.:|||:|::||..|||:|||:
Zfish    90 REVRIMKLLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 154

  Fly   174 EYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSG 238
            :|||.|.||||||||||||||..|.:||||||||..|.....|:||||||||||||||:||||.|
Zfish   155 QYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTLGNKLDTFCGSPPYAAPELFQGKKYDG 219

  Fly   239 PEVDSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYYVSIECESLIRKFLVLNPTQRT 303
            ||||.|||||:|||||||||||||.||||||:||||||||:|:|:|.:||:|::||||||||:|.
Zfish   220 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPTKRG 284

  Fly   304 SL-SAVMADRWINMGYEQGNGLRPFQEKPMDLHDVNRL------------SLLSNMGHKPRDVEQ 355
            || ..:|.|||:|:|:|. ..|:|:.|...|..|..|.            .::..||:...:::.
Zfish   285 SLEQQIMKDRWMNVGHED-EELKPYIEPQPDYKDPKRTGQHPSSAGGWKRDIMIRMGYSLDEIQD 348

  Fly   356 SLKNQKFDDIYCTYMLLDV-----------AKP-------------------------RST---A 381
            ||.|||::|:..||:|||.           |:|                         |||   :
Zfish   349 SLINQKYNDVMATYLLLDYRNSELDELSIKARPGTDITNNAQSPSHKGQRSTSNLKSRRSTDQSS 413

  Fly   382 CSEK-----------SGSSFRETPTAMPGSSRIPVPIAAPNVTISQVTFALDKSTPNRPAAT--- 432
            .|.|           ||||.:..|:.:........|..:.|..:|..| ...:::|....||
Zfish   414 VSSKRPQGDSKHIGSSGSSSKVPPSPLISGDHKKTPTPSTNSILSSGT-GRSRNSPITERATLGV 477

  Fly   433 -----SIRPMAPRLANALTPLPLTPPPKKYICCSASKAANPRRSEPSSIPQSAMPKKGVGSPVDV 492
                 |:.....|.:.|              ..:|..||:.|.....|:..||.|     ||.|
Zfish   478 QNGKDSLHTPGSRASTA--------------SAAAVLAASSRTRHHKSLSTSAHP-----SPPD- 522

  Fly   493 KTTLLSAQRKLAVNQKLTSASHQIRSPITQSPSQASECTRT-----------------PPTHFEM 540
                |.|.|....||:.     .:.||..|:.:.:|...||                 ..|..:.
Zfish   523 ----LHAHRPSTANQRA-----PVVSPSAQNINISSMADRTNFSRGVTSRSTFHAGQQRATRDQQ 578

  Fly   541 LDSTSTPLKVLKLVASNSQTPPSTENTNRPTRVGFFSKLSARFVRRSL 588
            ..:.:.|.....|...|||       ..|| ..|.|||.:::||||:|
Zfish   579 ASAYNDPSASPSLSHGNSQ-------VRRP-GTGIFSKFTSKFVRRNL 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78b	NP_001163587.1	PKc_like	63..314	CDD:304357	180/251 (72%)
		S_TKc	63..314	CDD:214567	180/251 (72%)
mark2a	XP_009293774.1	STKc_MARK	44..296	CDD:270974	180/251 (72%)
		S_TKc	44..296	CDD:214567	180/251 (72%)
		UBA_MARK2	314..367	CDD:270589	15/52 (29%)
		MARK2_C	683..781	CDD:213386

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24346
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910