Protein Alignment KP78b and 4921509C19Rik

DIOPT Version :9

• Sequence 1: NP_001163587.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_941057.1
• Gene: 4921509C19Rik / 381393
• MGIID: 2685851
• Length: 640
• Species: Mus musculus
• Alignment Length: 583
• Identity: 176/583 - (30%)
• Similarity: 278/583 - (47%)
• Gaps: 101/583 - (17%)

  Fly    63 YKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLYREVNIMKKLNHPNIVRLLQ 127
            |:|:.|||:|.|.:||||.||.|..:||||::.|:..|::.:.    |:.|||.|:||:|::||.
Mouse    24 YEILTTLGQGTFGEVKLASHLVTQTKVAIKILPKSRKNSLVQP----EIEIMKSLDHPHIIKLLH 84

  Fly   128 VIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHSKSIVHRDLKAENLL 192
            :|::.|.:::|:|:..||||.:.:.:.|.:.|.:...||:|||.|::|||.|.|||||||.||:|
Mouse    85 IIDTTRNIFIVLEHAVGGELMSRIEEFGYLAEVECHRLFKQLVYALQYCHEKGIVHRDLKPENIL 149

  Fly   193 LDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSGPEVDSWSLGVVLYTLVSGS 257
            ||.:..:|:.|||..|.......|.||||:.||.|||||..:.|.|...|.||||||||.:.:|.
Mouse   150 LDHRGNVKLTDFGLGTKIIMGQKLVTFCGTLPYCAPELFEDRGYDGRATDVWSLGVVLYFMATGC 214

  Fly   258 LPFDGTNLKELRDRVLRGKYRVPYYVSIECESLIRKFLVLNPTQRTSLSAVMADRWINMGYEQGN 322
            |||:|.:.:.::.:::.|||...:.:|.|...:|.|.|.:||.:|.::..:...:|
Mouse   215 LPFNGYSYEAIKQKIIAGKYPRSFSLSPELWEVIAKLLTVNPGERPTVHDIARFKW--------- 270

  Fly   323 GLRPFQE-KPMDL------H-DVNRLSLLSNMGHKPRDVEQSLKNQKFDDIYCTYMLL------- 372
             |:|..| .|..|      | |.:.:.|:..||:.|.::.:||:.:|||.:..||::|
Mouse   271 -LKPDNEASPASLGENIESHPDPSIMVLMGVMGYNPGEIRESLREKKFDQVMATYLMLKQQSAWE 334

  Fly   373 --DVAKPRSTACSE--KSGSSFRETPTAMPGSSRIPVPIAAPNVTISQVTFALDKSTPNRPAA-- 431
              ...||....|..  :|.....:..|::..:|.:|          :..||:|    ||...:
Mouse   335 NKTTKKPDPRLCDRMLRSTEPTIKNQTSVRRASSVP----------THSTFSL----PNESESLE 385

  Fly   432 ----TSIRPMAPRLANAL----TPLPLTPPPKKYICCSASKAANPRRS-----EPSSIPQSAMPK 483
                |::....|...|..    |||       ..||....:.|:.|||     |.|...:.:...
Mouse   386 KGKRTTMSHSMPPTRNCFNEETTPL-------HSICPQLVQKAHYRRSIWGETEISDTSEESSTG 443

  Fly   484 KGVGSP---VDVKTTLLSAQRKLAVNQKLTSASHQIRSPITQSPSQASECTR-----TPPTHFEM 540
            :.:..|   :....|.:...:..:...|...:|..:.|..|.......|.|.     .||.
Mouse   444 ESLEHPSLKIHTLQTSMGVSKAGSTYSKSKGSSQCVSSHHTSVEEDQCEGTNISREINPPL---- 504

  Fly   541 LDSTSTPLKVLK-----LVASNSQTPPSTENTNRPTRVGFFSKLSARFVRRSLHKGEKDISEQ 598
              |..:|.:.|.     :..:.|....:|:.|:.|     ||:..|        |||....:|
Mouse   505 --SPVSPQENLMGQLHIVTTAGSMDIMNTQVTSPP-----FSRKEA--------KGEGPALQQ 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78b	NP_001163587.1	PKc_like	63..314	CDD:304357	106/250 (42%)
		S_TKc	63..314	CDD:214567	106/250 (42%)
4921509C19Rik	NP_941057.1	STKc_AMPK-like	23..270	CDD:270905	106/249 (43%)
		UBA_MARK_Par1	290..328	CDD:270522	12/37 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	359..399		10/53 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	464..509		9/50 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	531..576		10/35 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	617..640

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810