Protein Alignment KP78b and Smok2a

DIOPT Version :9

• Sequence 1: NP_001163587.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_038769.1
• Gene: Smok2a / 27263
• MGIID: 1351487
• Length: 504
• Species: Mus musculus
• Alignment Length: 591
• Identity: 171/591 - (28%)
• Similarity: 281/591 - (47%)
• Gaps: 142/591 - (24%)

  Fly    46 RSSPKFQSYVNGNGYGVYKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQ----K 106
            ||.|.|...  .|.:..|:::.|:|.|...|||||.|..||..||:|:|.|       |:    .
Mouse    13 RSKPPFSEM--ENFHAQYEMLGTIGHGGSTKVKLARHRLTGTHVAVKMIPK-------REYWCKP 68

  Fly   107 LYREVNIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVS 171
            |..|..::...:||||:.||||||:::.:||:||...|..|:.::...|.::|.:||.||:||:|
Mouse    69 LMSEAELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGYLQEDEARALFKQLLS 133

  Fly   172 AIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKY 236
            ||.|||::.|||||||.:|:::::..::||.|||.....:|...|..|||:.|::|||:...:.|
Mouse   134 AINYCHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLGIQVKPGQKLNLFCGTYPFSAPEVLLSRPY 198

  Fly   237 SGPEVDSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYYVSIECESLIRKFLVLNPTQ 301
            .||::|.|:||||||.:|:|.:|||..::::||.:::.|||.||..:|::...||...:..||..
Mouse   199 DGPKIDVWTLGVVLYFMVTGKIPFDAASIEKLRKQIVAGKYSVPCRLSVKLHHLITLLMTDNPEL 263

  Fly   302 RTSLSAVMADRWINMGYEQGNGL--RPFQE----KPMDLHDVNRLSLLSNMGHKPRDVEQSLKNQ 360
            |.:::.||...|:.    :|:|:  .|.:|    ||    |...:..:.::|.:.:|:|.||:.:
Mouse   264 RPTVAEVMMHPWVT----KGSGVFPDPCEEQIPLKP----DPAIVKAMGHIGFQAQDIEDSLRQR 320

  Fly   361 KFDDIYCTYMLLDVAKPRSTACSEKSGSSFRETPTAMPGSSRIPVPIAAPNVTISQVTFALDKST 425
            ||::...:|.||  .|.....|..                     ||.|
Mouse   321 KFNETMASYCLL--KKQILKECDR---------------------PIRA---------------- 346

  Fly   426 PNRPAATSIRPMAPRLANALTPLP-LTPPPKKYICCSASKAANPRRSEPSSIPQSAMPKKGVGSP 489
                     :||.|    ::||.| |...|..::      ....|.:||:|:
Mouse   347 ---------QPMNP----SVTPFPSLVDTPTFHL------GLRRRETEPTSL------------- 379

  Fly   490 VDVKTTLLSAQRKLAVNQKLTSASHQ--------IRSPITQSPS--QASECTRTPP---THFEML 541
                  .|||.|:::|..:.||....        :..||..:|:  |...|||:.|   ::|.::
Mouse   380 ------RLSANRQMSVCGRSTSKKRDRSFSWPGVLSRPINITPTMDQTHTCTRSVPCINSNFCII 438

  Fly   542 DSTSTPLKVLKLVASNSQTPPSTENTNRPTR--------VGFFSKLSARFVR--------RSLHK 590
            ...|:.      .::...|..|.|  ::|.|        .|:.||:.....:        .:.|.
Mouse   439 HPNSSD------ESTEGHTSASAE--DKPVRSRGWPRGIKGWTSKIGNAMRKLCCCIPSNETSHL 495

  Fly   591 GEKDIS 596
            |::.:|
Mouse   496 GQRRVS 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78b	NP_001163587.1	PKc_like	63..314	CDD:304357	103/254 (41%)
		S_TKc	63..314	CDD:214567	103/254 (41%)
Smok2a	NP_038769.1	STKc_AMPK-like	27..275	CDD:270905	103/254 (41%)
		S_TKc	28..276	CDD:214567	103/254 (41%)
		UBA_MARK_Par1	295..334	CDD:270522	12/44 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	376..403		9/45 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	443..469		5/33 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810