Protein Alignment KP78b and Gm4922

DIOPT Version :9

• Sequence 1: NP_001163587.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_808374.1
• Gene: Gm4922 / 237300
• MGIID: 3644318
• Length: 497
• Species: Mus musculus
• Alignment Length: 495
• Identity: 156/495 - (31%)
• Similarity: 232/495 - (46%)
• Gaps: 111/495 - (22%)

  Fly    63 YKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLYR----EVNIMKKLNHPNIV 123
            |.::|||.:....:|:|..|..||..||:|        .:..|:.:.    ||.|||.|:|||||
Mouse    28 YTVLKTLSQHGTTEVRLCSHHLTGVTVAVK--------ALKYQRWWEPKVSEVEIMKMLSHPNIV 84

  Fly   124 RLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHSKSIVHRDLKA 188
            .||||||:|:.:||:||...|.:|.|.:.:...::|.:||.:|.||:|||.|||.:.:||||||.
Mouse    85 SLLQVIETEQNIYLIMEVAQGTQLHNRVQEARCLKEDEARSIFVQLLSAIGYCHGEGVVHRDLKP 149

  Fly   189 ENLLLDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSGPEVDSWSLGVVLYTL 253
            :|:::|:...:||.|||....|.|...||..||:..:..||:|.|..|.||:||.|:|||:||.:
Mouse   150 DNVIVDEHGNVKIVDFGLGARFMPGQKLERLCGAFQFIPPEIFLGLPYDGPKVDIWALGVLLYYM 214

  Fly   254 VSGSLPFDGTNLKELRDRVLRGKYRVPYYVSIECESLIRKFLVLNPTQRTSLSAVMADRWINMGY 318
            |:|..||.|:.|.|:...||:|:|.:||.:|.:..|:|...|..|..||.:...:::..|:..|
Mouse   215 VTGIFPFVGSTLSEISKEVLQGRYEIPYNLSKDLRSMIGLLLATNARQRPTAQDLLSHPWLQEG- 278

  Fly   319 EQGNGLRPFQEKPMDLH--------DVNRLSLLSNMGHKPRDVEQSLKNQKFDDIYCTYMLLDVA 375
                      ||.:..|        |.:.::.:.|:|...:|:.:|||::|||:...||.||
Mouse   279 ----------EKTITFHSNGDTSFPDPDIMAAMKNIGFHVQDIRESLKHRKFDETMATYNLL--- 330

  Fly   376 KPRSTACSE---------------------KSG-------------------SSFRETPTAMPGS 400
              |:.||.:                     .||                   ||..|......|.
Mouse   331 --RAEACQDDGNYVQTKLMNPGMPPFPSVTDSGAFSLPPRRRASEPSFKVLVSSTEEHQLRQTGG 393

  Fly   401 SRIPVP----------------IAAPNVTISQVTF--ALDKS--TPNRPAATSIRPMAPRLANAL 445
            :..|.|                :.||.:.:.:.|:  ..|.|  |.::...||   ..|..:...
Mouse   394 TNAPFPPKKTPTMGRSQKQKRAMTAPCICLLRNTYIDTEDSSFCTSSQAEKTS---SDPEKSETS 455

  Fly   446 TPLPLTPPP----KKYI--------CCSASKAANPRRSEP 473
            |..||||..    ||.|        ||:..:...||...|
Mouse   456 TSCPLTPRGWRKWKKRIVACIQTLCCCTLPQKKCPRSVHP 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78b	NP_001163587.1	PKc_like	63..314	CDD:304357	104/254 (41%)
		S_TKc	63..314	CDD:214567	104/254 (41%)
Gm4922	NP_808374.1	STKc_AMPK-like	27..274	CDD:270905	104/253 (41%)
		UBA_MARK_Par1	293..330	CDD:270522	12/36 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	383..410		4/26 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	439..460		4/23 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810