Protein Alignment KP78b and mark2b

DIOPT Version :9

• Sequence 1: NP_001163587.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_009301419.1
• Gene: mark2b / 100005996
• ZFINID: ZDB-GENE-080215-4
• Length: 790
• Species: Danio rerio
• Alignment Length: 643
• Identity: 265/643 - (41%)
• Similarity: 362/643 - (56%)
• Gaps: 105/643 - (16%)

  Fly    42 SSGG--RSSPKFQSYV-NGNGY---GVYKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALN 100
            :.||  .|:|:.::.| ....|   |.|:::||:|||||||||||.|:.|.:|||:|:||||.||
Zfish    22 AKGGVRSSAPRCRNAVATAEEYPHIGNYRLLKTIGKGNFAKVKLARHVLTSKEVAVKIIDKTQLN 86

  Fly   101 TIARQKLYREVNIMKKLNHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVL 165
            :.:.||::|||.|||.|||||||:|.:|||:::||||||||.||||:|:|||.:|||:|::||..
Zfish    87 SSSLQKVFREVRIMKLLNHPNIVKLFEVIETDKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK 151

  Fly   166 FRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAPLETFCGSPPYAAPEL 230
            |||:|||::|||.|.||||||||||||||..|.:||||||||..|.....|:|||||||||||||
Zfish   152 FRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPEL 216

  Fly   231 FRGKKYSGPEVDSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYYVSIECESLIRKFL 295
            |:||||.|||||.|||||:|||||||||||||.||||||:||||||||:|:|:|.:||:|::|||
Zfish   217 FQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL 281

  Fly   296 VLNPTQRTSL-SAVMADRWINMGYEQGNGLRPFQEKPMDLHDVNRLSLLSNMGHKPRDVEQSLKN 359
            :||||:|.|| ..:|.|||:|:|||. :.|:|:.|...|..|..|..::..||....::|.||..
Zfish   282 ILNPTKRGSLEQQIMKDRWMNVGYED-DDLKPYIEPQPDYKDPRRTDIMLQMGFSQEEIEDSLVK 345

  Fly   360 QKFDDIYCTYMLLDVAKPRSTACSEKSGSSFRETPTAMPGSSRIPVPIAAPNVTISQVTFALDKS 424
            ||::::..||:|||.   |::...|....|.:..|.:...:|..|.|......::|.......:|
Zfish   346 QKYNEVMATYLLLDY---RNSELDEGVNLSLKSRPGSDLTNSNAPSPPHKVQRSVSSTQKPARRS 407

  Fly   425 T-----PNRPAATS---IRPMAPRLANALTPLPLTPPPKKYICCSASKAANPRRSEPSSIPQSAM 481
            |     ..||...:   :.....:.:::.|.:    ||...|.....|::.|..:...|...|
Zfish   408 TDQGSYSKRPQGENKHGVEDSGRKGSSSSTKV----PPSPVISSERKKSSTPSTNSILSTGTS-- 466

  Fly   482 PKKGVGSPVDVKTTLLSAQRKLAVNQKLTSASHQIRSPITQSPSQASECTRTPPTHFEMLDSTST 546
              :...||:..:.||.....|.:::...:.||.....|:..|.|.:|. ||    |.:.| |||.
Zfish   467 --RSRNSPISERATLGVQNGKDSLSTPGSRASTASAGPVLSSSSSSSR-TR----HHKSL-STSA 523

  Fly   547 PLKVLKLVASNSQTPP-----------------STENTN-------------------------- 568
            ......|.:.....||                 .|:.||
Zfish   524 HPSPADLHSHRPSDPPQRAPGASPSAHNISSAAGTDRTNFPRGVPTRNTFHLGQQRGARDQQGSP 588

  Fly   569 ------------------RPTRVGFFSKLSARFVRRSL---------HKGEKDISEQG 599
                              ||...|.|||.:::||||:|         ::||.  .|:|
Zfish   589 YHGAPASPSLSHGNSQQRRPAASGIFSKFTSKFVRRNLSFRFPRRSPYEGEG--QEEG 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KP78b	NP_001163587.1	PKc_like	63..314	CDD:304357	176/251 (70%)
		S_TKc	63..314	CDD:214567	176/251 (70%)
mark2b	XP_009301419.1	STKc_MARK	48..301	CDD:270974	176/252 (70%)
		S_TKc	49..301	CDD:214567	176/251 (70%)
		UBA_MARK2	319..360	CDD:270589	14/40 (35%)
		AMPKA_C_like	691..789	CDD:302605

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24346
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910