Protein Alignment CG5214 and LAT1

DIOPT Version :9

• Sequence 1: NP_650064.1
• Gene: CG5214 / 41360
• FlyBaseID: FBgn0037891
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_014328.3
• Gene: LAT1 / 855653
• SGDID: S000005015
• Length: 482
• Species: Saccharomyces cerevisiae
• Alignment Length: 489
• Identity: 125/489 - (25%)
• Similarity: 191/489 - (39%)
• Gaps: 103/489 - (21%)

  Fly    53 NRCQEATRLLTWQGIHTTSSLWSEQTVNVPPFADSIAEGDI-KFTCKVGDSFAADEAVMEIETDK 116
            :|....||.|..| :...:|......:.:|..:.::.:|:: .:|.|.||..:..|.:.||||||
Yeast    12 SRSSVLTRSLRLQ-LRCYASYPEHTIIGMPALSPTMTQGNLAAWTKKEGDQLSPGEVIAEIETDK 75

  Fly   117 TTVAVPAPFSGTLTDILVKDG------------------DTVKPGQALFKIKPGAAPAKAAAPAA 163
            ..:.......|.|..|||.:|                  |.  |....||::...:.:|.:..|.
Yeast    76 AQMDFEFQEDGYLAKILVPEGTKDIPVNKPIAVYVEDKADV--PAFKDFKLEDSGSDSKTSTKAQ 138

  Fly   164 APAPAAPKAAPAPAAAPKPAPPPPAAGAPKPPPPPPPKAAPRPPPPAPVAALKPAV--------- 219
            ...|.|.|...|||...|.:.|     ..|......|:......|.|...||:..:
Yeast   139 PAEPQAEKKQEAPAEETKTSAP-----EAKKSDVAAPQGRIFASPLAKTIALEKGISLKDVHGTG 198

  Fly   220 --------------------------AQVKVPPADGSRQILG-------TRSEQRVKMNRMRLKI 251
                                      |....|.|..|....|       |.|.:.|.::.||..|
Yeast   199 PRGRITKADIESYLEKSSKQSSQTSGAAAATPAAATSSTTAGSAPSPSSTASYEDVPISTMRSII 263

  Fly   252 AARLKDAQNTCAMLTTFNEVDMSYAMDFRKQNLDAFTK-KYGIKFGFMSIFAKASAYALQDQPVV 315
            ..||..:..........:::.:|..:..| |:|:|... ||  |.....:..||...|.:..|..
Yeast   264 GERLLQSTQGIPSYIVSSKISISKLLKLR-QSLNATANDKY--KLSINDLLVKAITVAAKRVPDA 325

  Fly   316 NAVIDGTDIVYRDY--VDISVAVATPRGLVVPVIRNVEGMNYADIEIALAGLADKARRDAITVED 378
            ||.....:.|.|.:  ||:|||||||.||:.|:::|.|....:.|...:..|..:||.:.:..|:
Yeast   326 NAYWLPNENVIRKFKNVDVSVAVATPTGLLTPIVKNCEAKGLSQISNEIKELVKRARINKLAPEE 390

  Fly   379 MDGGTFTISNGGVFGSL-MGTPIINPPQSAILGMHGI---------------FERPIAVKGEVKI 427
            ..|||..|||.|:..:: |.|.|||||||.||.:..:               |:..:.:.|
Yeast   391 FQGGTICISNMGMNNAVNMFTSIINPPQSTILAIATVERVAVEDAAAENGFSFDNQVTITG---- 451

  Fly   428 RPMMYIALTYDHRIIDGREAVLFLRKIKAAVENP 461
                    |:|||.|||.:...|::::|..:|||
Yeast   452 --------TFDHRTIDGAKGAEFMKELKTVIENP 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5214	NP_650064.1	lipoyl_domain	77..149	CDD:133458	22/90 (24%)
		sucB	78..468	CDD:273565	119/464 (26%)
		2-oxoacid_dh	255..462	CDD:278621	68/226 (30%)
LAT1	NP_014328.3	PDHac_trf_mito	36..482	CDD:273567	119/464 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810