DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5214 and AT4G26910

DIOPT Version :9

Sequence 1:	NP_650064.1	Gene:	CG5214 / 41360	FlyBaseID:	FBgn0037891	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_567761.1	Gene:	AT4G26910 / 828798	AraportID:	AT4G26910	Length:	464	Species:	Arabidopsis thaliana

Alignment Length:	417	Identity:	201/417 - (48%)
Similarity:	256/417 - (61%)	Gaps:	46/417 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 GIHTTSSLWSE--------------QTVN--VPPFADSIAEGDI-KFTCKVGDSFAADEAVMEIE 113
            ||..::||.|.              .||.  ||...:||.:|.: .|..|.|:...||||:.:||
plant    66 GISRSASLVSSTLQRWVRPFSAETGDTVEAVVPHMGESITDGTLATFLKKPGERVQADEAIAQIE 130

  Fly   114 TDKTTVAVPAPFSGTLTDILVKDGDTVKPGQALFKIKPGAAPAKAAAPAAAPAPAAPKAAPAPAA 178
            |||.|:.:.:|.||.:.:.||.:||||:||..:..|......|....| :...|......|:|.|
plant   131 TDKVTIDIASPASGVIQEFLVNEGDTVEPGTKVAIISKSEDTASQVTP-SQKIPETTDTKPSPPA 194

  Fly   179 APKPAP---PPPAAGAPK-PPPPPPPKAAPRPPPPAPVAALKPAVAQVKVPPADGSRQILGTRSE 239
            ..|..|   ..|.|..|| |..|||||.:.:.|               ::||.:         .|
plant   195 EDKQKPRVESAPVAEKPKAPSSPPPPKQSAKEP---------------QLPPKE---------RE 235

  Fly   240 QRVKMNRMRLKIAARLKDAQNTCAMLTTFNEVDMSYAMDFRKQNLDAFTKKYGIKFGFMSIFAKA 304
            :||.|.|:|.::|.||||:|||.|:|||||||||:..|..|.|..|||.:|:|:|.|.||.|.||
plant   236 RRVPMTRLRKRVATRLKDSQNTFALLTTFNEVDMTNLMKLRSQYKDAFYEKHGVKLGLMSGFIKA 300

  Fly   305 SAYALQDQPVVNAVIDGTDIVYRDYVDISVAVATPRGLVVPVIRNVEGMNYADIEIALAGLADKA 369
            :..|||.||||||||||.||:||||||||:||.|.:||||||||..:.||:|:||..:..||.||
plant   301 AVSALQHQPVVNAVIDGDDIIYRDYVDISIAVGTSKGLVVPVIRGADKMNFAEIEKTINSLAKKA 365

  Fly   370 RRDAITVEDMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAVKGEVKIRPMMYIA 434
            ....|::::|.||:||:|||||:|||:.|||||||||||||||.|..||:.|.|.|..|||||:|
plant   366 NEGTISIDEMAGGSFTVSNGGVYGSLISTPIINPPQSAILGMHSIVSRPMVVGGSVVPRPMMYVA 430

  Fly   435 LTYDHRIIDGREAVLFLRKIKAAVENP 461
            ||||||:|||||||.|||::|..||:|
plant   431 LTYDHRLIDGREAVYFLRRVKDVVEDP 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5214	NP_650064.1	lipoyl_domain	77..149	CDD:133458	31/74 (42%)
		sucB	78..468	CDD:273565	196/391 (50%)
		2-oxoacid_dh	255..462	CDD:278621	135/207 (65%)
AT4G26910	NP_567761.1	PLN02226	1..464	CDD:177871	201/417 (48%)
		lipoyl_domain	93..166	CDD:133458	30/72 (42%)
		2-oxoacid_dh	251..462	CDD:278621	135/207 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	295	1.000	Domainoid score	I350
eggNOG	1	0.900	-	-		E1_COG0508
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	378	1.000	Inparanoid score	I540
OMA	1	1.010	-	-		QHG62730
OrthoDB	1	1.010	-	-		D850255at2759
OrthoFinder	1	1.000	-	-		FOG0003446
OrthoInspector	1	1.000	-	-		otm3066
orthoMCL	1	0.900	-	-		OOG6_101182
Panther	1	1.100	-	-	O	PTHR43416
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2345
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840