Protein Alignment CG5214 and Dlat

DIOPT Version :9

• Sequence 1: NP_650064.1
• Gene: CG5214 / 41360
• FlyBaseID: FBgn0037891
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_112287.1
• Gene: Dlat / 81654
• RGDID: 619859
• Length: 632
• Species: Rattus norvegicus
• Alignment Length: 557
• Identity: 135/557 - (24%)
• Similarity: 197/557 - (35%)
• Gaps: 166/557 - (29%)

  Fly    72 SLWSEQTVNVPPFADSIAEGDI-KFTCKVGDSFAADEAVMEIETDKTTVAVPAPFSGTLTDILVK 135
            ||...|.|.:|..:.::..|.| ::..|.|:..:..:.:.|:||||.||...:.....:..|||.
  Rat    78 SLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVP 142

  Fly   136 DGDTVKPGQALFKI---KPGAAPAKAAAPAAAPAPAAPKAAPAPAAAPKPAPPPPAAGAP----- 192
            :|....|..::..|   ||....|.......: |.||.:|||||||||..||..|:|.||
  Rat   143 EGTRDVPVGSIICITVEKPQDIEAFKNYTLDS-ATAATQAAPAPAAAPAAAPAAPSASAPGSSYP 206

  Fly   193 ----------------------------------------------------------------- 192
                                                                             
  Rat   207 VHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGT 271

  Fly   193 ------------------------------------KPPPPPPPKAA----PRPPPPAPVAA--- 214
                                                .|||.|||.||    |:|..|.|.||
  Rat   272 RDVPLGTPLCIIVEKQEDIAAFADYRPTEVTSLKPQAPPPVPPPVAAVPPIPQPLAPTPSAAPAG 336

  Fly   215 ------LKPAVAQVKVPPADGSRQILGTRSEQR-------------------------------- 241
                  :.|...::.........|:.||..|.|
  Rat   337 PKGRVFVSPLAKKLAAEKGIDLTQVKGTGPEGRIIKKDIDSFVPTKAAPAAAAAAPPGPRVAPTP 401

  Fly   242 ------VKMNRMRLKIAARLKDAQNTCAMLTTFNEVDMSYAMDFRKQNLDAFTKKYGIKFGFMSI 300
                  :.::.:|..||.||..::.|........:|:|...:..||: |:...:..| |......
  Rat   402 AGVFIDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKE-LNKMLEGKG-KISVNDF 464

  Fly   301 FAKASAYALQDQPVVNAVIDGTDIVYRDYVDISVAVATPRGLVVPVIRNVEGMNYADIEIALAGL 365
            ..||||.|....|..|:....|.|.....||:||||:||.||:.|::.|........|...:..|
  Rat   465 IIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSL 529

  Fly   366 ADKARRDAITVEDMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFERPIAVKGE--VKIR 428
            |.|||...:...:..||||||||.|:||....:.||||||:.||.:....::.|....|  ..:.
  Rat   530 ASKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLIPADNEKGFDVA 594

  Fly   429 PMMYIALTYDHRIIDGREAVLFLRKIKAAVENPAIIV 465
            .:|.:.|:.|||::||.....:|.:.|..:|.|..::
  Rat   595 SVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPVTML 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5214	NP_650064.1	lipoyl_domain	77..149	CDD:133458	19/72 (26%)
		sucB	78..468	CDD:273565	132/551 (24%)
		2-oxoacid_dh	255..462	CDD:278621	67/208 (32%)
Dlat	NP_112287.1	lipoyl_domain	83..156	CDD:133458	19/72 (26%)
		lipoyl_domain	209..283	CDD:133458	0/73 (0%)
		PDHac_trf_mito	211..632	CDD:273567	92/423 (22%)
		E3_binding	342..375	CDD:280908	6/32 (19%)
		2-oxoacid_dh	421..632	CDD:278621	68/213 (32%)
		Catalytic. /evidence=ECO:0000250	456..632		61/177 (34%)
		CoA-binding. /evidence=ECO:0000250	600..611		5/10 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810