DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5214 and Pdhx

DIOPT Version :9

Sequence 1:NP_650064.1 Gene:CG5214 / 41360 FlyBaseID:FBgn0037891 Length:468 Species:Drosophila melanogaster
Sequence 2:NP_001381465.1 Gene:Pdhx / 311254 RGDID:1566332 Length:502 Species:Rattus norvegicus


Alignment Length:468 Identity:133/468 - (28%)
Similarity:202/468 - (43%) Gaps:82/468 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 WQGIHTTSSLWSEQTVNVPPFADSIAEGDI-KFTCKVGDSFAADEAVMEIETDKTTVAVPAPFSG 127
            |:..|.|..|.....:.:|..:.::..|:| |:..|.|::.:|.:|:.||||||..|.:.|...|
  Rat    43 WRWFHGTQLLQDPIKILMPSLSPTMERGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDANDDG 107

  Fly   128 TLTDILVKDG-DTVKPGQAL-FKIKPG------------AAPAKAAAPAAAPAPAAPKAAPAPAA 178
            .|..|:|::| ..:|.|..: ..::.|            :||.....|.|.|.|:.....|.||.
  Rat   108 ILAKIVVEEGAKNIKLGSLIALMVEEGEDWKHVEIPKDVSAPPPVPKPPAPPQPSPQTQTPCPAR 172

  Fly   179 APKPAPPPP----------------------AAGAPK-----------------------PPPPP 198
            ..:....||                      .|..|:                       .|.|.
  Rat   173 KERTVGTPPRLRLSPAARNILEKHSLDASQGTATGPRGVFTKEDALRLVELKQMGKIAEFRPAPG 237

  Fly   199 PPKAAPRPPPPAPVAAL---KPAVAQVKVPPADGSRQILGTRSEQRVKMNRMRLKIAARLKDAQN 260
            ||.....|.||.|.|.|   :|.:..|.:|   |.....||.:|  :..:.:|..||.||.::::
  Rat   238 PPSTLSAPVPPQPTAGLSYPRPMIPPVSIP---GQPNAAGTFTE--IPASNIRKVIAKRLTESKS 297

  Fly   261 TCAMLTTFNEVDMSYAMDFRKQNLDAFTKKYGIKFGFMSIFAKASAYALQDQPVVNAVIDGTDIV 325
            |..........|:...:..|:..:     |..||........:|:|..|:..|.||...||....
  Rat   298 TVPHAYATANCDLGAVLKVRRDLV-----KDDIKVSVNDFIIRAAAVTLKQMPGVNVTWDGEGPK 357

  Fly   326 YRDYVDISVAVATPRGLVVPVIRNVEGMNYADIEIALAGLADKARRDAITVEDMDGGTFTISNGG 390
            :...|||||||||.:||:.|:|::....:..:|..|:..|:.|||...:..|:..||:|:|||.|
  Rat   358 HLPSVDISVAVATDKGLITPIIKDAAAKDIREIADAVKVLSKKARDGKLLPEEYQGGSFSISNLG 422

  Fly   391 VFGSLMGTPIINPPQSAILGMHGIFERPIA-----VKGEVKIRPMMYIALTY--DHRIIDGREAV 448
            :||....|.:|||||:.||.: |.| ||:.     .:|..::|....|.:|.  |.|::|...|.
  Rat   423 MFGIDEFTAVINPPQACILAV-GRF-RPVLKLTEDEEGNPQVRQHQLITVTMSSDSRMVDDELAT 485

  Fly   449 LFLRKIKAAVENP 461
            .||...||.:|||
  Rat   486 KFLETFKANLENP 498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5214NP_650064.1 lipoyl_domain 77..149 CDD:133458 23/74 (31%)
sucB 78..468 CDD:273565 129/454 (28%)
2-oxoacid_dh 255..462 CDD:278621 71/214 (33%)
PdhxNP_001381465.1 PDHac_trf_mito 57..501 CDD:273567 129/454 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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