DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scpr-A and PI16

DIOPT Version :9

Sequence 1:	NP_650062.1	Gene:	scpr-A / 41358	FlyBaseID:	FBgn0037889	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	232	Identity:	58/232 - (25%)
Similarity:	83/232 - (35%)	Gaps:	69/232 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 KLILNLFNELRNNVAGGKIEGLPKAVRMAKMSWCEELSHLALLNVKTCESLPDKCRSTERFAYAG 124
            :|::.|.|..|..|:       |.|..|..|.|.|||:..|....:.|....:|.|...     |
Human    34 RLMVELHNLYRAQVS-------PTASDMLHMRWDEELAAFAKAYARQCVWGHNKERGRR-----G 86

  Fly   125 QNNALFQYSGAETEYTDAEIIKEEIENWFAERS--NASPEILASFPEELPNKAVTKFTIAVAEKN 187
            :|  ||..:   .|..|..:..||   |..||.  |.|....:      |.:....:|..|..|.
Human    87 EN--LFAIT---DEGMDVPLAMEE---WHHEREHYNLSAATCS------PGQMCGHYTQVVWAKT 137

  Fly   188 THVGCAAVRFSRDFYNHF-------------VLTCNF-ATSNIVGQPVY---TPGEKATTG--CK 233
            ..:||.         :||             :|.||: ...|:.|:..|   ||..:..:|  ||
Human   138 ERIGCG---------SHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHCK 193

  Fly   234 NR----YGAAYDYPNLCY---------AKEIYDNEKV 257
            |.    .|:..|..:|.|         |.|..|:.|:
Human   194 NSLCEPIGSPEDAQDLPYLVTEAPSFRATEASDSRKM 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scpr-A	NP_650062.1	SCP_euk	60..212	CDD:240180	41/167 (25%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	41/166 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920